DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7156 and Snx29

DIOPT Version :9

Sequence 1:	NP_650697.1	Gene:	CG7156 / 42187	FlyBaseID:	FBgn0038588	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	XP_006522729.1	Gene:	Snx29 / 74478	MGIID:	1921728	Length:	819	Species:	Mus musculus

Alignment Length:	404	Identity:	83/404 - (20%)
Similarity:	132/404 - (32%)	Gaps:	131/404 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   328 TTDGG-SVSHLECPWNQ--LARYKVLQILQDR------------VMQVQCVTKSQQPA------A 371
            |:|.| ..:.|.|..|:  |.|| :..:|.||            ||..:  ..|..|.      :
Mouse   109 TSDAGRGRAWLRCALNEHSLERY-LHMLLADRARLSTFYEDWSFVMDEE--RSSMLPTMAAGLNS 170

  Fly   372 IMKGVEKPASHSLTQSIFLPQQVPYMVQLLAYFQSEQKIFLLLRQAEGGMLYDYLQSYTPTSSKS 436
            |:..:.........||.|    .|.:..||.  :|.|.:..||:::..|| ...|:..|.:|:.|
Mouse   171 ILFAINIDNKDLNGQSKF----APTVSDLLK--ESTQNVTSLLKESTQGM-SSLLREITASSAVS 228

  Fly   437 VNYGELFPSDQEPEEKEAEEPPLTSDSDVSDLVRSSQQLLKSVTN---------------TLSNL 486
            :..        :||::....|.::.:..|....:..::..|.|||               ||..:
Mouse   229 ILI--------KPEQETDPLPVISKNVHVDTRCKRERRRRKKVTNIVSFDDDEEEQGTGDTLKKM 285

  Fly   487 QAGVVTPKRNKKVDQNRIRSKPIPE----------QCLRQWACELAIAIHSLHGKGVILRDLHMG 541
            .....:.:.|.  |::.:......|          |....|..:.|    ||:|:
Mouse   286 PGTAESSEENS--DRSSVNIMAAFEGTFGPNSNGSQSSSSWKIDSA----SLNGE---------- 334

  Fly   542 NILLGAKGQLLLTYFYQNEGLTSDDNYVHKALNLEAV---------ANHFVAPERPLTFRSDWWS 597
               ||          ||...:.|.|:.|.:  |.|..         ..|..:|:|.|       .
Mouse   335 ---LG----------YQKLDVKSIDDDVDE--NEEDAYRSPLGRGHTGHAESPDRTL-------D 377

  Fly   598 YGVVLYQLLLGVPYKVTHPGQLDL-------------YGCVQYPSESLEISDHAKDLLEQLLQLS 649
            ....|.|:....|.:|.| |..|.             ||....|..|||.....::      .:.
Mouse   378 GNACLAQVHGWAPLQVLH-GDADADTDVLFPVSGVGSYGAADAPVGSLENGTGTEN------HII 435

  Fly   650 PELRLDYDQLQAHP 663
            ||..|.|.:..:.|
Mouse   436 PEPGLRYSREASSP 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7156	NP_650697.1	PX_SNX15_like	8..124	CDD:132791
		MIT_SNX15	241..315	CDD:239140
		PKc_like	343..665	CDD:304357	77/388 (20%)
Snx29	XP_006522729.1	RUN	44..177	CDD:367169	17/70 (24%)
		Smc	<472..>634	CDD:224117
		PX_RUN	662..779	CDD:132810
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900