DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7156 and snx15

DIOPT Version :9

Sequence 1:	NP_650697.1	Gene:	CG7156 / 42187	FlyBaseID:	FBgn0038588	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_001093667.1	Gene:	snx15 / 734054	XenbaseID:	XB-GENE-492800	Length:	342	Species:	Xenopus tropicalis

Alignment Length:	364	Identity:	97/364 - (26%)
Similarity:	138/364 - (37%)	Gaps:	115/364 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 FTVTDTQEHKGGYTIYKITSIVFPRSVPQALTCLVVWKRFHDVKRLHRELSRRHKSL-----QLP 71
            :.||||:.:..|:|.||:|:....:..||.:..::||||:.|.|:||.|||..|::|     :.|
Frog    15 YNVTDTRTNPKGFTEYKVTAQFISKKNPQDVKEVLVWKRYSDFKKLHGELSYTHRNLFQRCQEFP 79

  Fly    72 GKLPVPTDSTYFKRFDAAVIQRRKEYILQLLDFAAQHPALYKCSTFTQFFQETPSPNGSPLKKLY 136
               |.|. :..|.||:|.||:.|::....:|.|....||||               |...||..:
Frog    80 ---PFPR-AQVFGRFEAPVIEERRQAAEDMLKFTVNIPALY---------------NSPQLKDFF 125

  Fly   137 VERSLRLQTEDNGCGSGGSETGTCAGAIADICDKLDLPYDPHDAGGITPLDPR----CDKEQTNN 197
            .|..:..|.|..                 |..|.|.||         |||.|.    |..|....
Frog   126 REGEVSQQAEGQ-----------------DSFDALVLP---------TPLTPEPVRCCSPEDLEE 164

  Fly   198 ESQAKETEIELE-TK--------------------QEPKTDV------------ALTKRDYLRLL 229
            .:....|.:..| ||                    :|.:.|:            :||..| |.|.
Frog   165 ATDCSATVVPTEVTKPVEDPVIDEPSQIDLLFDLCEEHEDDIVAQDRITCTRQQSLTHND-LALF 228

  Fly   230 TPM-----ASIES----------------------DDSDYIYEAALEFSHAVQAEVNLEYAEAHE 267
            .|.     .|:||                      :...||.:|..:...|::.|...:|.||..
Frog   229 DPCFAEGPPSVESHLNLLSLGDEQIVETAALFTNEEQGAYISQATEDVQRAMEKEAAGDYPEAFR 293

  Fly   268 RYKHGVDLLLNGAKQDSSEERRFIAKAKIAKYLARAEEI 306
            .|:..||.||.|.|.|..|:||.....:.|:||:.||.|
Frog   294 LYRSAVDTLLKGVKDDPCEDRRNAVTRRTAEYLSHAENI 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7156	NP_650697.1	PX_SNX15_like	8..124	CDD:132791	40/116 (34%)
		MIT_SNX15	241..315	CDD:239140	25/66 (38%)
		PKc_like	343..665	CDD:304357
snx15	NP_001093667.1	PX_SNX15	11..128	CDD:132821	43/131 (33%)
snx15	NP_001093667.1	MIT_SNX15	267..340	CDD:239140	25/66 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I7971
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D135297at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm49287
Panther	1	1.100	-	-	O	PTHR15508
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020