DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7156 and Snx15

DIOPT Version :9

Sequence 1:	NP_650697.1	Gene:	CG7156 / 42187	FlyBaseID:	FBgn0038588	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_081188.1	Gene:	Snx15 / 69024	MGIID:	1916274	Length:	337	Species:	Mus musculus

Alignment Length:	370	Identity:	94/370 - (25%)
Similarity:	144/370 - (38%)	Gaps:	111/370 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 WIHSFTVTDTQEHKGGYTIYKITSIVFPRSVPQALTCLVVWKRFHDVKRLHRELSRRHKSL-QLP 71
            ::..:||:|.:.|..|||.||:|:....:..|:.:..:|||||:.|.::||.:|:..|::| :..
Mouse     9 FLRHYTVSDPRTHPKGYTEYKVTAQFISKKDPEDIKEVVVWKRYSDFRKLHGDLAYTHRNLFRRL 73

  Fly    72 GKLPVPTDSTYFKRFDAAVIQRRKEYILQLLDFAAQHPALYKCSTFTQFFQETPSPNGSPLKKLY 136
            .:.|....:..|.||:|:||:.|::....||.|....|||.......:||:     .|...:...
Mouse    74 EEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVPIPALNNSPQLKEFFR-----GGEVTRPSE 133

  Fly   137 VERSLR--------------------LQTEDNGCGSGGSETGTCAGAIADICDKLDLPYDPHDAG 181
            |.|.||                    |..|..|                  .::|::|.||
Mouse   134 VSRDLRILPPPLIPTPPPDEARLLQPLPAERRG------------------QEELEVPVDP---- 176

  Fly   182 GITPLDP---------RCDKEQTNNESQAK----ETE-------------------------IEL 208
              .|..|         .||..:..:.|.|:    |.|                         ||:
Mouse   177 --LPSSPAQEALDLLFSCDSTEEASSSLARGPLSEAELALFDPYSKEESTGPSPTHTGELAAIEV 239

  Fly   209 ETK---QEPKTDVALTKRDYLRLLTPMASIESDDSD------YIYEAALEFSHAVQAEVNLEYAE 264
            |:|   |||              ..|....|.:..|      |:.:|....:.|::.|....||.
Mouse   240 ESKRLDQEP--------------WEPGGQEEEEAEDGEPAPAYLGQATELITQALRNEKAGAYAA 290

  Fly   265 AHERYKHGVDLLLNGAKQDSSEERRFIAKAKIAKYLARAEEIHAN 309
            |.:.|:.||.:||.|...|.|..||...|.|.|:||.|||.:|.:
Mouse   291 ALQGYQDGVHILLQGVSGDPSPARREGVKKKAAEYLKRAEMLHTH 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7156	NP_650697.1	PX_SNX15_like	8..124	CDD:132791	38/116 (33%)
		MIT_SNX15	241..315	CDD:239140	27/75 (36%)
		PKc_like	343..665	CDD:304357
Snx15	NP_081188.1	PX_domain	9..126	CDD:383026	38/121 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	133..156		4/22 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	244..270		7/39 (18%)
		MIT_SNX15	267..337	CDD:239140	26/69 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	84	1.000	Domainoid score	I8270
eggNOG	1	0.900	-	-		E1_KOG0603
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D135297at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.780