Protein Alignment CG7156 and Rps6ka6

DIOPT Version :10

• Sequence 1: NP_650697.1
• Gene: CG7156 / 42187
• FlyBaseID: FBgn0038588
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_080225.2
• Gene: Rps6ka6 / 67071
• MGIID: 1914321
• Length: 860
• Species: Mus musculus
• Alignment Length: 470
• Identity: 101/470 - (21%)
• Similarity: 185/470 - (39%)
• Gaps: 144/470 - (30%)

  Fly   250 FSHAVQAEVNLEYAEAHERYKHGVDLLLNGAKQDSSEERRFIAKAKIAKYLARAEEIHANFLAND 314
            ||.|.:|.: |.:|...:.:.. .|:.:.|:  .||.|.:.:...|.|..:.|.   |.....||
Mouse    89 FSRAPEAAM-LPFAPVEDPWDQ-EDMEVFGS--TSSSEPQVVFTMKNAATVMRE---HERKEVND 146

  Fly   315 ---------------CPTKKLQFQLSLDTTDGGSVSHLECPWNQL--ARYKVLQIL-QDRVMQVQ 361
                           |..::|..::.:       ..|::..:.:.  |::.:|::| |....:|.
Mouse   147 LKMVDEPMEEGEPVSCRREELVKEIPI-------TQHVKEGYEKADPAQFDLLKVLGQGSFGKVF 204

  Fly   362 CVTKSQQPAA----IMKGVEKPA-------SHSLTQSIFLPQQVPYMVQLLAYFQSEQKIFLLLR 415
            .|.|...|.|    .||.:.|.:       ...:.:.|.:....|::|:|...||:|.|::|:|
Mouse   205 LVRKKTGPDAGQLYAMKVLRKASLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLIL- 268

  Fly   416 QAEGGMLYDYLQSYTPTSSKSVNYGELFPSDQEPEEKEAEEPPLTSDSDVSDLVRSSQQLLKSVT 480
                    |:|:.           |::|                         .|.|:::|
Mouse   269 --------DFLRG-----------GDVF-------------------------TRLSKEVL---- 285

  Fly   481 NTLSNLQAGVVTPKRNKKVDQNRIRSKPIPEQCLRQWACELAIAIHSLHGKGVILRDLHMGNILL 545
                                        ..|:.::.:..|||:|:..||..|::.|||...||||
Mouse   286 ----------------------------FTEEDVKFYLAELALALDHLHRLGIVYRDLKPENILL 322

  Fly   546 GAKGQLLLTYFYQNEGLTSDDNYVHKALNLEAVANHFVAPE----RPLTFRSDWWSYGVVLYQLL 606
            ...|.:.||.|    ||:.:.....|..........::|||    |..:..:|||||||:::::|
Mouse   323 DEIGHIKLTDF----GLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEML 383

  Fly   607 LG-VPYKVTHPGQ-LDL-----YGCVQYPSESLEISDHAKDLLEQLLQLSPELRL---DYDQLQA 661
            .| :|::.....: :::     .|..|:      :|..|:.||..|.:.:|..||   ..::::.
Mouse   384 TGTLPFQGKDRNETMNMILKAKLGMPQF------LSAEAQSLLRMLFKRNPANRLGSEGVEEVKR 442

  Fly   662 HPFFKGIDWQAVLEQ 676
            |.||..|||..:.::
Mouse   443 HAFFASIDWNKLYKR 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7156	NP_650697.1	PX_SNX15_like	8..124	CDD:132791
		MIT_SNX15	241..315	CDD:239140	17/79 (22%)
		Protein Kinases, catalytic domain	343..665	CDD:473864	76/349 (22%)
Rps6ka6	NP_080225.2	STKc_RSK_N	193..507	CDD:270734	79/352 (22%)
		STKc_RSK_C	542..828	CDD:270993