Protein Alignment CG7156 and sgk3

DIOPT Version :10

• Sequence 1: NP_650697.1
• Gene: CG7156 / 42187
• FlyBaseID: FBgn0038588
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001103937.1
• Gene: sgk3 / 564523
• ZFINID: ZDB-GENE-070424-62
• Length: 486
• Species: Danio rerio
• Alignment Length: 678
• Identity: 118/678 - (17%)
• Similarity: 207/678 - (30%)
• Gaps: 292/678 - (43%)

  Fly    16 DTQEHKGGYTIYKITSIVFPRSVPQALTCLVVWKRFHDVKRLHRELSRRHKSLQLPGKLPVPTDS 80
            :.::.|..||:||:...|....       ..|::|:.:..:|:..|.::..:|    .|.:|...
Zfish    17 EQRDKKKRYTVYKVMVSVGRHE-------WFVFRRYAEFDKLYNTLKKQFPAL----NLKIPAKR 70

  Fly    81 TYFKRFDAAVIQRRKEYILQLLDFAAQHPALYKCSTFTQFFQETPSPNGSPLKKLYVERSLRLQT 145
            .:...||...|::|:..:.:.:.....|..|  ||              .|..|::::
Zfish    71 IFGDNFDPEFIKQRRAGLHEFIQRIVSHSQL--CS--------------HPDVKVFLQ------- 112

  Fly   146 EDNGCGSGGSETGTCAGAIADICDKLDLPYDPHDAGGITPLDPRCDKEQTNNESQAKETEIELET 210
                                                          .::..|.|...|.|
Zfish   113 ----------------------------------------------MDKAKNFSDGSEDE----- 126

  Fly   211 KQEPKTDVALTKRDYLRLLTPMASIESDDSDYIYEAALEFSHAVQAEVNL-EYAEAHERYKHGVD 274
                                       ||.          |::....:|| ..|..|
Zfish   127 ---------------------------DDK----------SNSTSRNINLGPSANPH-------- 146

  Fly   275 LLLNGAKQDSSEERRFIAKAKIAKYLARAEEIHANFLANDCPTKKLQFQLSLDTTDGGSVSHLEC 339
                 ||....:..:.|.|....|.|                       |:....||      :|
Zfish   147 -----AKPTDFDFLKVIGKGSFGKVL-----------------------LAKRKRDG------KC 177

  Fly   340 PWNQLARYKVLQILQDRVMQVQCVTKSQQPAAIMKGVEKPASHSLTQSIFLPQQV--PYMVQLLA 402
                    ..:::||.:|:    :.:.:|            .|.:.:...|.:.|  |::|.|..
Zfish   178 --------YAIKVLQKKVI----LNRREQ------------KHIMAERNVLLKNVKHPFLVGLHY 218

  Fly   403 YFQSEQKIFLLLRQAEGGMLYDYLQSYTPTSSKSVNYGELFPSDQEPEEKEAEEPPLTSDSDVSD 467
            .||:..|::.:|....||.|:.:||
Zfish   219 SFQTTDKLYFVLDFVNGGELFFHLQ---------------------------------------- 243

  Fly   468 LVRSSQQLLKSVTNTLSNLQAGVVTPKRNKKVDQNRIRSKPIPEQCLRQWACELAIAIHSLHGKG 532
                                                 :.:..||...:.:..|:|.|:..||...
Zfish   244 -------------------------------------KERTFPEPRAKFYIAEMASALGYLHSLN 271

  Fly   533 VILRDLHMGNILLGAKGQLLLTYF-YQNEGLTSDDNYVHKALNLEAVANHFVAPE----RPLTFR 592
            ::.|||...||||.::|.::||.| ...||::..|.........|     ::|||    :|....
Zfish   272 IVYRDLKPENILLDSQGHIVLTDFGLCKEGISQADTTTTFCGTPE-----YLAPEVLRKQPYDNT 331

  Fly   593 SDWWSYGVVLYQLLLGVP---YKVTHPGQLDLYGCVQYPSESLE--ISDHAKDLLEQLLQLSPEL 652
            .|||..|.|||::|.|:|   .:.||    ::|..:.:....:.  .|..|..:|:.||:.....
Zfish   332 VDWWCLGSVLYEMLYGLPPFYSRDTH----EMYDNILHKELVMRPGASTAAWSILQTLLEKDHTR 392

  Fly   653 RL----DYDQLQAHPFFKGIDWQAVLEQ 676
            ||    |:::::.|.||..|:|.. |||
Zfish   393 RLGYRDDFNEVKEHEFFSSINWYD-LEQ 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7156	NP_650697.1	PX_SNX15_like	8..124	CDD:132791	21/107 (20%)
		MIT_SNX15	241..315	CDD:239140	11/74 (15%)
		Protein Kinases, catalytic domain	343..665	CDD:473864	67/337 (20%)
sgk3	NP_001103937.1	PX_CISK	6..114	CDD:132780	23/176 (13%)
		STKc_SGK3	155..480	CDD:270755	82/405 (20%)