DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7156 and snx13

DIOPT Version :9

Sequence 1:	NP_650697.1	Gene:	CG7156 / 42187	FlyBaseID:	FBgn0038588	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	XP_021323912.1	Gene:	snx13 / 503733	ZFINID:	ZDB-GENE-050306-12	Length:	966	Species:	Danio rerio

Alignment Length:	522	Identity:	98/522 - (18%)
Similarity:	159/522 - (30%)	Gaps:	208/522 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 VKRLHRELSRRHKSLQLPGKLPVPTDSTYFKRFDAAVIQRRKEYILQLLDFAAQHPALYKCSTFT 118
            |.||.::|::..         |.|      :.||.  |||:      :.|...:|...|..
Zfish   467 VTRLAQKLNKED---------PTP------EIFDE--IQRK------VYDMMLKHEHYYPS---- 504

  Fly   119 QFFQETPSPNGSPLKKLYV----------ERSLRLQTEDNGCGSGGSETGT--------CAGAI- 164
              |::.|         |||          |.|.|...:.:|....||.||:        .:|::
Zfish   505 --FRQHP---------LYVRMLAELDMLKEPSYRGSDDGDGESFNGSPTGSINLSLDDLSSGSVD 558

  Fly   165 ------ADICDKLDLPYDPHDAGGITPLDPRCDKEQTNNESQAKETEIELETKQEPKTDVALTKR 223
                  |.|.|..|...:|....|:      |:   .:.::.|..|...:....:...|...|.|
Zfish   559 ESVQLHAFISDTADAFLNPLPVAGV------CN---DHGKTYALYTITVIRKNSDGSEDTWKTYR 614

  Fly   224 DYLRLLTPMASIESDDSDYIYEAALEFSHAVQAEVNLEYAEAHERYKHGVDLLLNGAKQDSSEER 288
            .|           ||..|:......:|......                  |.|.|.|..::.:|
Zfish   615 RY-----------SDFHDFHMRITEQFESLAPI------------------LKLPGKKTFNNMDR 650

  Fly   289 RFIAKAK-----IAKYLARAEEIHA---------NFLANDCPTK-KLQFQLSLDTTDGGSVSHLE 338
            .|:.|.|     ..:.|...|.:.|         :||.|...:| |.:|...:||
Zfish   651 EFLEKRKKDLNAYLQLLLNPEMVKACPILMPYVYDFLENKAYSKGKREFARKMDT---------- 705

  Fly   339 CPWNQLARYKVLQILQDRVMQVQCVTKSQQPAAIMKGVEKPAS----------HSLTQSIFLPQQ 393
                      .:..|:..:..|....|| .|.::.:||.|.::          ..:.||||   :
Zfish   706 ----------FVNPLRSSMRNVSNAVKS-LPDSLAEGVSKVSADMGRMSEKLGQDIKQSIF---K 756

  Fly   394 VPYMVQLLAYFQSEQKIFLLLRQAEGGMLYDYLQSYTPTSSKSVNYGELFPSDQEPE--EKEAEE 456
            ||.::|                                            .||.:||  ...|:.
Zfish   757 VPPLIQ--------------------------------------------KSDIDPEHCRVSAQL 777

  Fly   457 PPLTSDS-----------DVSDLVRSSQQLLKSVTNTLSNLQAGVVTPKRNKKVDQNRIRSKPIP 510
            .....|:           :|.||...:|.|.:::.|.|..|.........|:|: .:.:.:...|
Zfish   778 DDNVDDNIPLRVMLLLMDEVFDLKDRNQWLRRNIKNLLQQLIKATYGDTINRKI-VDHVDNMTSP 841

  Fly   511 EQ 512
            ||
Zfish   842 EQ 843

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7156	NP_650697.1	PX_SNX15_like	8..124	CDD:132791	15/69 (22%)
		MIT_SNX15	241..315	CDD:239140	16/87 (18%)
		PKc_like	343..665	CDD:304357	34/193 (18%)
snx13	XP_021323912.1	PXA	98..284	CDD:321992
		RGS	378..513	CDD:321993	18/83 (22%)
		PX_SNX13	559..690	CDD:132783	30/168 (18%)
		Nexin_C	806..915	CDD:312222	9/39 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900