DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7156 and snx15

DIOPT Version :9

Sequence 1:	NP_650697.1	Gene:	CG7156 / 42187	FlyBaseID:	FBgn0038588	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_001104707.1	Gene:	snx15 / 393352	ZFINID:	ZDB-GENE-040426-1377	Length:	398	Species:	Danio rerio

Alignment Length:	393	Identity:	97/393 - (24%)
Similarity:	158/393 - (40%)	Gaps:	100/393 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 FTVTDTQEHKGGYTIYKITSIVFPRSVPQALTCLVVWKRFHDVKRLHRELSRRHKSL-----QLP 71
            |:|||.:.|:.|:|.||:|:....::.|:.:..:|||||:.::|:||.||:..|::|     :.|
Zfish    14 FSVTDPRTHEKGHTEYKVTARFVSKTQPENVKEVVVWKRYTELKKLHGELAYTHRNLFRRQEEFP 78

  Fly    72 GKLPVPTDSTYFKRFDAAVIQRRKEYILQLLDFAAQHPALYKCSTFTQFFQE------------- 123
               |.|. :..|.|||.|||:.|:.....:|.|....||||......:||::
Zfish    79 ---PFPR-AQVFGRFDEAVIEERRNAAEAMLLFTTNIPALYNSPQLKEFFRDGEVRRPLETAVIS 139

  Fly   124 -------TPSPNGS-------------PLKKLYVERSLRL------------------------- 143
                   .|.|..|             |::...::.:.||
Zfish   140 TSLPPPLIPLPERSADLLAEEETGTEAPIQAQELDSNQRLTDLTQPEIAVEALSDTRSSPTQETQ 204

  Fly   144 -----------QTEDNGCGSGGSETGTCAGAIADICDKL--DLPYDPHDAGGITPLDPRCDKEQT 195
                       :|||:......:.||.|..|..|.....  ::|..|.|.  :...|...|....
Zfish   205 TDAEIQELTEKETEDDSTTHENNHTGQCTAATDDSTTHASPEMPGSPIDQ--LEEFDALFDSGLE 267

  Fly   196 NNESQA----KETEIELETKQEP--KTDVALTKRDYLRLLT-PMASIESDDS----DYIYEAALE 249
            :...:|    .:|::.:   .:|  |.|.......:..||: |:......||    .|:|:|..|
Zfish   268 DYSFKAPPLLSDTDLAI---FDPCVKEDQPYGSPSHAELLSAPLCGSNGTDSAVDVSYVYQANEE 329

  Fly   250 FSHAVQAEVNLEYAEAHERYKHGVDLLLNGAKQDSSEERRFIAKAKIAKYLARAEEIHANFLAND 314
            .:.|.:.|....|:.|.:||:..||:.:.|.:.|...:||...|.|||:.|..||.:    |:..
Zfish   330 LNAAQEQEREGNYSTAVQRYRAAVDIFMKGVQGDVDLKRRDAVKRKIAEVLEHAERL----LSIQ 390

  Fly   315 CPT 317
            .||
Zfish   391 TPT 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7156	NP_650697.1	PX_SNX15_like	8..124	CDD:132791	42/136 (31%)
		MIT_SNX15	241..315	CDD:239140	24/73 (33%)
		PKc_like	343..665	CDD:304357
snx15	NP_001104707.1	PX_SNX15	10..127	CDD:132821	42/116 (36%)
snx15	NP_001104707.1	MIT_SNX15	321..395	CDD:239140	26/77 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	82	1.000	Domainoid score	I8374
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D135297at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25822
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15508
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.880