DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7156 and Snx13

DIOPT Version :9

Sequence 1:	NP_650697.1	Gene:	CG7156 / 42187	FlyBaseID:	FBgn0038588	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	XP_006240084.1	Gene:	Snx13 / 362731	RGDID:	1309778	Length:	1144	Species:	Rattus norvegicus

Alignment Length:	506	Identity:	95/506 - (18%)
Similarity:	164/506 - (32%)	Gaps:	197/506 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IHSFTVTDT--------------QEHKGGYTIYKITSIVFPRSVPQALTCLVVWK---RFHDVKR 56
            :|:: ::||              .:|...|.:|.||  |..||    |....:||   |:.|...
  Rat   737 LHAY-ISDTVYADYDPYAVAGVCNDHGKTYALYAIT--VHRRS----LNTEEMWKTYRRYSDFHD 794

  Fly    57 LHRELSRRHKS----LQLPGKLPVPTDSTYFKRFDAAVIQRRKEYI---LQLL---DFAAQHPAL 111
            .|..::.:.::    |:||||       ..|...|...:::||:.:   ||||   :.....|||
  Rat   795 FHMRITEQFENLSSILKLPGK-------KTFNNMDRDFLEKRKKDLNAYLQLLLTPEMLKASPAL 852

  Fly   112 YKCSTFTQFFQETPSPNG------------SPLKKLYVERSLRLQTEDNGCGSGGSETGTCAGAI 164
            ..|  ...|.:......|            :||:     .|:|                ..:.|:
  Rat   853 AHC--VYDFLENKAYSKGKGDFARKMDTFVNPLR-----NSMR----------------NVSNAV 894

  Fly   165 ADICDKLDLPYDPHDAGGITPLDPRCDKEQTNNESQAKETEIELETKQE-PKTDVALTKRD---- 224
            ..:.|.|        |.|:|        :.::|..:..| .:..:.||. .|....:||.|
  Rat   895 KSLPDSL--------AEGVT--------KMSDNVGRMSE-RLGQDIKQSFFKVPPLITKTDSDPE 942

  Fly   225 YLRLLTPMASIESDDSDYIYEAALEFSHAVQAEVNLEYAEAHERYKHGVDLLLNGAKQDSSEERR 289
            :.|:     |.:.||:             |...:.|.           |.|||.....|..|..:
  Rat   943 HCRV-----SAQLDDN-------------VDDNIPLR-----------VMLLLMDEVFDLKERNQ 978

  Fly   290 FIAK--AKIAKYLARAEEIHANFLANDCPTKKLQFQLSLDTTDGGSVSHLECPWNQLARYKVLQI 352
            ::.:  ..:.:.|.||       ...|...:|:             |.|::  |
  Rat   979 WLRRNIKNLLQQLIRA-------TYGDTINRKI-------------VDHVD--W----------- 1010

  Fly   353 LQDRVMQVQCVTKSQQPAAIMK---------GVEKPASHSLTQSIFLPQQVPYMVQLLAYFQSEQ 408
                      :|..:|.|..:|         |:...|:....::|.:..::....:|.|....|.
  Rat  1011 ----------MTSPEQVADSVKRFRDALWPNGILAEAAPCRDKAIRMRTRIAGKTKLFAVMPDEL 1065

  Fly   409 KIFL--------LLR--------QAEGGMLYDYLQSYTPTSSKSVNYGELF 443
            |..:        :||        |....|:|.:|:.:..|......:.|||
  Rat  1066 KHIIGAETTRKGILRVFEMFQHNQLNRRMVYVFLEGFLETLFPQYKFRELF 1116

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7156	NP_650697.1	PX_SNX15_like	8..124	CDD:132791	35/141 (25%)
		MIT_SNX15	241..315	CDD:239140	11/75 (15%)
		PKc_like	343..665	CDD:304357	21/126 (17%)
Snx13	XP_006240084.1	PXA	273..460	CDD:295366
		RGS_SNX13	553..687	CDD:188674
		PX_SNX13	733..863	CDD:132783	35/141 (25%)
		Nexin_C	979..1087	CDD:285792	21/150 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900