DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7156 and CG5439

DIOPT Version :9

Sequence 1:	NP_650697.1	Gene:	CG7156 / 42187	FlyBaseID:	FBgn0038588	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_609607.1	Gene:	CG5439 / 34710	FlyBaseID:	FBgn0032476	Length:	520	Species:	Drosophila melanogaster

Alignment Length:	482	Identity:	94/482 - (19%)
Similarity:	166/482 - (34%)	Gaps:	169/482 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   266 HERYKHGVDLLLNGAKQ---DSSEERRFI--------AKAKIAKYLARAEEIHA-----NFLAND 314
            |||.:: :||     ||   :....|.||        ..:.:..:|:..|::|.     :.|.||
  Fly   125 HERQRY-MDL-----KQIWTNVGRGRAFIRATLNEKRLHSHVLTWLSDEEQLHRFYTPWSLLLND 183

  Fly   315 CPTKKLQ----------FQLSLDTTD-------GGSVSHLE-------CPWNQLARYKVLQILQD 355
            ...|||.          |.|::|||:       ..||:..|       .|...:.|.|...|..:
  Fly   184 EAAKKLPEIVDSLSDVLFALNVDTTELNAPRRSTPSVAVKEEPIIFTTSPVPVVGRQKRPGIAVE 248

  Fly   356 RVMQVQCVTKSQQPAAIMKGVEKP------ASHSLTQSIFLPQQVPYMVQLLAYFQSEQKIFLLL 414
            |  .::||:.::.....:|.:|..      :..|:.|.:..||:   .|.|..:...|.::
  Fly   249 R--PIECVSSTEDLLGALKPIESVEVQQILSKESIEQELAQPQE---EVNLGPFDPIEPEL---- 304

  Fly   415 RQAEGGMLYDYLQSYTPTSSKSVNYGELFPSDQEPEEKEAEEPPLTSDSDVSDLVRSSQQ-LLKS 478
                     ::|::..|.....|...||:....:...:.::     |.|..:.|..|.|| .|:.
  Fly   305 ---------EFLKTPLPDIGAHVGESELYEDRSDTSSQWSK-----SSSSANCLANSQQQAALEE 355

  Fly   479 VTNTLSNLQAGVVTPKRNKKVDQNRIRSKPIPEQCLRQWACELAIAIHSLHGKGVILRDLHMGNI 543
            ..|.|:                          |:|.   ..|..:|..||..:.:|.|
  Fly   356 HVNQLN--------------------------ERCA---LLETRVAELSLQNRLLIRR------- 384

  Fly   544 LLGAKGQLLLTYFYQNEGLTSD----DNYV----H-KALNLEAVANHFVAPERPLTFRS--DWWS 597
                     ||..::..|:...    .|::    | |....:...:|:.. |..:|.|.  :.|:
  Fly   385 ---------LTKQFEETGIDPSSSLCSNFLITIPHVKLAKTQRSGSHYTY-EVHITMRQRLEHWT 439

  Fly   598 Y------GVVLYQLLLGVPYKVTHPGQLDLYGCVQYPSES-------LEISDHAKDLLEQLLQLS 649
            :      ...|::.||     .|||    :...|::|.:.       :.:.:..:.|...||.|.
  Fly   440 FFRRYSEFYKLHKSLL-----KTHP----VVSAVEFPPKKHFGNMNLVFVEERRQQLQIYLLNLV 495

  Fly   650 PELRLDYDQLQA----------HPFFK 666
            ..|    .|::|          .|||:
  Fly   496 ETL----PQVEACKSKAELQKVFPFFR 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7156	NP_650697.1	PX_SNX15_like	8..124	CDD:132791
		MIT_SNX15	241..315	CDD:239140	15/64 (23%)
		PKc_like	343..665	CDD:304357	64/362 (18%)
CG5439	NP_609607.1	RUN	64..206	CDD:280855	21/86 (24%)
CG5439	NP_609607.1	PX_RUN	404..520	CDD:132810	25/129 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900