DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7156 and snz

DIOPT Version :9

Sequence 1:	NP_650697.1	Gene:	CG7156 / 42187	FlyBaseID:	FBgn0038588	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_001284993.1	Gene:	snz / 31704	FlyBaseID:	FBgn0029976	Length:	1117	Species:	Drosophila melanogaster

Alignment Length:	416	Identity:	83/416 - (19%)
Similarity:	135/416 - (32%)	Gaps:	124/416 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   291 IAKAKIAKYLAR------AEEIHANFLANDCPTKKLQFQLSLDTTDGGSVSHLE---------CP 340
            :.|.|:...:.|      .::||...|..|  ..|:   :::|..:..:| |||         ..
  Fly   166 VTKPKLINDVVREDLWNAIQKIHERALRMD--AAKI---IAVDMVNRVTV-HLEKIRIAEARAAE 224

  Fly   341 WNQLARYKVLQILQDRVMQVQCVTKSQQPAAIM---KGVEKP-----ASHSLTQSIFLPQQVPYM 397
            .|....:.....|.|...:::.:.|..:...|:   :|...|     .|..|:..||.|     |
  Fly   225 TNTPPVFSTNSYLADEEKEMEFLRKLCEIMVILLLPRGYSLPPLKVLLSEILSYKIFFP-----M 284

  Fly   398 VQLLA---YFQSEQKIFLLLRQAEGGM---LYDYLQSYTPTSSKSVNYGELFPSDQEPEEKEAEE 456
            :::|.   |...:....:..|.|...|   .|:|..|:........|.|.|            ||
  Fly   285 IKMLTAPDYINQKVVQNIETRLAAAAMSKRSYEYAASFEDFLKIINNSGNL------------EE 337

  Fly   457 PPLTSDSDVSDLVRSSQQLLKSVTNTLSNLQAGVVTPKRNKKVDQNR-------------IRSKP 508
            ..|...|.|:||:.::         |:.|||       |.|.:|.:.             :|.|.
  Fly   338 LSLIRKSIVNDLMHAT---------TMQNLQ-------RAKGLDPDHEDHSLSKSELTAAVRLKR 386

  Fly   509 IPEQ-CLRQWACELAIAIHSLHGKGVILRDLHMGNILLGAKGQLLLTYFYQNEGLTSDDNYVHKA 572
            ...| .:.:..||..:|....:|......||.:..||..|.|:...|.|.:             .
  Fly   387 YVRQLTMAKGECEKNLAKFGWNGNYSSDIDLTLVEILNTAVGRRYFTLFLE-------------P 438

  Fly   573 LNLEAVANHFVAPERPLTFRSDWWSYGVVLYQLLLGVPYKVTHP------GQLDLYGCVQYPSES 631
            |...|:...::|.|.                       .|..|.      |....|..::.|...
  Fly   439 LKASALIGFYLAVEE-----------------------IKHAHKSASHQLGTEIFYTYIRVPKSE 480

  Fly   632 LEISDHAKDLLEQLLQLSPELRLDYD 657
            ::|..|.:.|:|..|....|..:.||
  Fly   481 IQIDKHERKLIETFLLGDAEPDIFYD 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7156	NP_650697.1	PX_SNX15_like	8..124	CDD:132791
		MIT_SNX15	241..315	CDD:239140	6/29 (21%)
		PKc_like	343..665	CDD:304357	69/349 (20%)
snz	NP_001284993.1	PXA	142..299	CDD:280373	28/143 (20%)
		RGS_SNX25	422..531	CDD:188675	23/121 (19%)
		PX_SNX25	645..788	CDD:132788
		Nexin_C	882..987	CDD:285792
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900