Protein Alignment CG7156 and Snx25

DIOPT Version :10

• Sequence 1: NP_650697.1
• Gene: CG7156 / 42187
• FlyBaseID: FBgn0038588
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001419741.1
• Gene: Snx25 / 306471
• RGDID: 1310150
• Length: 986
• Species: Rattus norvegicus
• Alignment Length: 760
• Identity: 152/760 - (20%)
• Similarity: 248/760 - (32%)
• Gaps: 242/760 - (31%)

  Fly     9 IHSFTVTDTQEHKGGYTIYKITSIVFPRSVPQALTCLVVWKRFHDVKRL---------------- 57
            |.||  ...:.|||..:....|.::..|::.:.:..|.|.|:..: ||:
  Rat   359 ISSF--PQLKRHKGKESAAMKTDLLRARNMKRYINQLTVAKKQCE-KRIRILGGPAYDQQEDGVS 420

  Fly    58 -HRELSRRHKSLQLPGKLPVP----TDSTYFKRFDAAVI-----------QRRKEYILQLLDFAA 106
             ..|..:..|.||....:..|    ...||.:|.|...:           ...|..|.||:.
  Rat   421 DEGEGPQSQKILQFEDIMTNPFYRERFGTYMERIDKRALVGFWESVEHLKNANKNEIPQLVS--- 482

  Fly   107 QHPALYKCSTFTQFFQETPSPNGSPLKKLYVERSLRLQTEDNGCGSGGSETGTCAGAIADICDKL 171
                    ..:..||.|:        |::.||:||..:.:....|:.|.|  ..:....|:.|.|
  Rat   483 --------EMYQNFFVES--------KEIPVEKSLYKEIQQCLVGNKGIE--VFSKIQGDVYDVL 529

  Fly   172 DLPYDP------------HDAGGITPLDPR--CDKEQTNNESQAKETEIELETKQEPKTDVALTK 222
            ...|.|            |:....|| |.:  ..|::..:..:|.|..:|..:........|:.|
  Rat   530 RDRYYPSFLVSDLYEKLIHEEEEETP-DSQLASGKDELGSGGEAGEEVVEGTSGVSDPASFAVIK 593

  Fly   223 RDYLRLLTPMASIESDDSDYIYEAALEFSHAVQAEVNLEYAEAHERY---KHGVDLLLNGAKQDS 284
               ||.|       |:..:|..:|.....:|.:.:..:......|..   |...||.|:.|:.|.
  Rat   594 ---LREL-------SEKLEYKRQALSSIQNAPKPDKKIISKLKDEILVIEKECTDLQLHMARTDW 648

  Fly   285 SEERRFIAKAKIAKYLARAEEIHANFLANDCPTKKLQFQLSLDTTDGGSVSHLECPWNQLARYKV 349
            ..|...:.||.|..    ||....|.....|...::..|      :.|.|....  |....|...
  Rat   649 WCEHLGLWKASITS----AEVTEENGEQMPCYFVRVNLQ------EVGGVETKN--WTVPRRLSE 701

  Fly   350 LQILQDRVMQVQCVTKSQQPAAIMKGVEKPASHSLT-QSI---FLPQQVPYMVQLLAYFQSEQKI 410
            .|.|..::.  :||..       :|.|:.|:...|. :||   ||.:....:.:.|....|::::
  Rat   702 FQNLHRKLS--ECVPS-------LKKVQLPSLSKLPFKSIDHKFLEKSKNQLNKFLQNLLSDERL 757

  Fly   411 FLLLRQAEGGMLY-------DYLQ----SYTPTSSKSVNYGELFPSD-QEPEEKEAEEPPLTSDS 463
            |    |:|.  ||       |||:    ....||....::.|..|.| ...:|:|.||     ||
  Rat   758 F----QSEA--LYAFLSPSPDYLKVIDVQGKKTSFSLSSFLEKLPRDFFSHQEEEIEE-----DS 811

  Fly   464 DVSDLVRSSQQLLKSVTNTLSNLQAGVVTPKRNKKVDQNRIRSKPIPEQC---------LR---Q 516
            |:||.                           ...||.   :...:.|.|         ||   :
  Rat   812 DLSDY---------------------------GDDVDG---KKDALAEPCFMLIGEIFELRGMFK 846

  Fly   517 WACELAIAIHSLHGKGVILRDLHMGNILLGAKGQLLLTYFYQNEGLTSDDNYVHKALNLEAVANH 581
            |.....||          |..:..|..:              |:.:....|::..    |.:..:
  Rat   847 WVRRTLIA----------LVQVTFGRTI--------------NKQIRDTVNWIFS----EQMVVY 883

  Fly   582 FVAPERPLTFRSDWWSYGVVL-------------------YQLLLGVP---------YKVTHPGQ 618
            :::     .||..:|..|.:.                   .:||..:|         ....| |.
  Rat   884 YIS-----AFRDAFWPNGKLAPPTRIRSEAQSQETKQRAQQKLLENIPDTLQSLVGQQNARH-GI 942

  Fly   619 LDLYGCVQYPSESLEISDHAKDLLEQLL--QLSPELRLDYDQLQA 661
            :.::..:|    ....:.|...:|.:||  :|.||||...|||:|
  Rat   943 IKIFKALQ----ETRANKHLLYVLMELLLTELCPELRAHLDQLKA 983

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7156	NP_650697.1	PX_SNX15_like	8..124	CDD:132791	28/146 (19%)
		MIT_SNX15	241..315	CDD:239140	17/76 (22%)
		Protein Kinases, catalytic domain	343..665	CDD:473864	74/377 (20%)
Snx25	NP_001419741.1	PXA	148..303	CDD:460484
		RGS	437..545	CDD:470619	25/128 (20%)
		PX_SNX25	648..770	CDD:132788	32/148 (22%)
		Nexin_C	847..953	CDD:462541	18/143 (13%)