Protein Alignment CG7156 and Snx14

DIOPT Version :10

• Sequence 1: NP_650697.1
• Gene: CG7156 / 42187
• FlyBaseID: FBgn0038588
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001346887.2
• Gene: Snx14 / 244962
• MGIID: 2155664
• Length: 946
• Species: Mus musculus
• Alignment Length: 727
• Identity: 124/727 - (17%)
• Similarity: 207/727 - (28%)
• Gaps: 294/727 - (40%)

  Fly    44 CLVVWKRFHD-----------VKRLHRELSRRHKSLQLPGKLPVPTDSTYFKRFDAAVIQRRKE- 96
            ||.| :.|:|           :..||.||.:.:|:..|...:    |...|..|....|||..|
Mouse   366 CLTV-EEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESI----DKIRFDPFIVEEIQRIAEG 425

  Fly    97 -YI-------LQLLDFAAQHPALYKCSTFTQFF-------------QETPSPNGSPLKKLYVERS 140
             ||       ::.|..|.:|......:.||..|             .|:|:.|..     :...|
Mouse   426 PYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSK-----FNRGS 485

  Fly   141 LRL----QTEDNGCGSGGSETGTCAGAIADICDKLDLPYDPHDAGGITPLDPRCDKEQTNNESQA 201
            |.|    .|:..|...|.|..|:....:                                    .
Mouse   486 LSLDDFRSTQKRGESFGISRIGSKIKGV------------------------------------F 514

  Fly   202 KETEIELETKQEPKTDVALTKRDYLRLLTPMASIESDDSDYIYE--AALEFSHAVQA-------- 256
            |.|.:|                   ..:.|...:...:.|:|.|  ..:|....|:|
Mouse   515 KSTTME-------------------GAVLPNYGVAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPR 560

  Fly   257 -----EVNLEYAEAHERYKHGVDLLLNGAKQDSSEERRFIAKAKIAKYLARAEEIHANFLANDCP 316
                 ::::.|.:..|               |.|.||:           .:.|.|..
Mouse   561 NLAAWKISIPYVDFFE---------------DPSSERK-----------EKKERIPV-------- 591

  Fly   317 TKKLQFQLSLDTTDGGSVSHLECPWNQLARYKVLQILQDRVMQVQ-CVTKSQQPAAIMKGVEKPA 380
                 |.:.::..|..:|.|....|:...||....:|:.::.:.. ....:|.|:   |.:..|.
Mouse   592 -----FCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGTFPDAQLPS---KRIIGPK 648

  Fly   381 SHSLTQS------IFLPQQVPY----MVQLLAYFQSEQKIFLLLRQAEGGMLYDYLQSYTPTSSK 435
            ::...:|      .:|.:.|.:    ..||||.|.|          ..||.. .:|....|
Mouse   649 NYEFLKSKREEFQEYLQKLVQHPELSNSQLLADFLS----------PNGGET-QFLDKILP---- 698

  Fly   436 SVNYGELF---PSDQEPEEKEAEEPPLTSDSDVSDLVRSSQQLLKSVTNTLSNLQAGVVTPKRNK 497
            .||.|::.   |.....|:.:..||                 .:.|..|:..:
Mouse   699 DVNLGKIIKSVPGKLMKEKGQHLEP-----------------FIMSFINSCES------------ 734

  Fly   498 KVDQNRIRSKPIPEQCLRQWACELAIAIHSLHGKGVILRDLHMGNILLGAKGQLLLTYFYQNEGL 562
                    .||.|.:      .||.|...:......:..||...|....           :|...
Mouse   735 --------PKPKPSR------PELTILSPTSENNKKLFNDLFKNNANRA-----------ENTER 774

  Fly   563 TSDDNYVHKALNLEAVANHFVAPERPLTFRSDWWSYGVVLYQLLLGVPYKVTHPGQLDLYG---- 623
            ..:.||..:.:.::.|.::.:...|.:....||      |:.||:|.  ::.....|::|.
Mouse   775 KQNQNYFMEVMTVDGVYDYLMYVGRVVFQVPDW------LHHLLMGT--RILFKNTLEMYTDYYL 831

  Fly   624 -------------------------CVQYPSESLEISDH-AKDLLEQLLQLSPEL---------- 652
                                     |......||:.... ||...|:::...|:|
Mouse   832 QCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLIVKCIGEETK 896

  Fly   653 ----RLDYDQLQ 660
                ||.:|.||
Mouse   897 YESIRLLFDGLQ 908

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7156	NP_650697.1	PX_SNX15_like	8..124	CDD:132791	26/112 (23%)
		MIT_SNX15	241..315	CDD:239140	14/88 (16%)
		Protein Kinases, catalytic domain	343..665	CDD:473864	64/376 (17%)
Snx14	NP_001346887.2	PXA	130..299	CDD:460484
		RGS_SNX14	340..466	CDD:188677	26/104 (25%)
		PX_SNX14	564..686	CDD:132787	29/173 (17%)
		Nexin_C	807..911	CDD:462541	20/110 (18%)