DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7156 and Rps6kl1

DIOPT Version :10

Sequence 1:NP_650697.1 Gene:CG7156 / 42187 FlyBaseID:FBgn0038588 Length:681 Species:Drosophila melanogaster
Sequence 2:NP_001351244.1 Gene:Rps6kl1 / 238323 MGIID:2443413 Length:545 Species:Mus musculus


Alignment Length:550 Identity:161/550 - (29%)
Similarity:232/550 - (42%) Gaps:143/550 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   227 RLLTPMASIESDDSDYIYEAALEFSHAVQAEVNLEYAEAHERYKHGVDLLLNGAKQDSSEERRFI 291
            |:.|..|.:..  .||:.:||.:...|::.:|:.:|..|...|::|||:||.|...|.::|||..
Mouse    36 RVATGTADVTK--RDYLVDAATQIHLALERDVSEDYEAAFNHYQNGVDVLLRGVHVDPNKERREA 98

  Fly   292 AKAKIAKYLARAEEIHANFLANDCPTKKLQFQLSLDTTDGGSVS--------------HLECPWN 342
            .|.||.|||.|||||               |...|..|.|...|              .|.....
Mouse    99 VKLKITKYLRRAEEI---------------FNCHLQRTLGSGASPNTGFSSLRLRPIRTLSSALE 148

  Fly   343 QLARYKVLQILQDRVMQVQCVTKSQQPAA----IMKGVEKPASHSLTQS--IFLPQQVPYMVQLL 401
            ||...:|:.|::    :||.|   |.||.    |:|.:  |..|.:::.  ..:|..||||.:||
Mouse   149 QLKGCRVVGIIK----KVQVV---QDPATGGTFIVKSL--PRCHMVSRERLTIIPHGVPYMTKLL 204

  Fly   402 AYFQSEQKIFLLLRQAEGGMLYDYLQS-----YTPTSSKSVNY---------------GELFPSD 446
            .||.||..|||.|...:||.|:.:|.|     |:..:|.||..               .||.|..
Mouse   205 RYFVSEDSIFLHLEHVQGGTLWSHLLSQDHFQYSGLNSGSVQEKSQAQLSTRLSLMTPAELTPGH 269

  Fly   447 QEPEEKEAEEPPLTSDSDVSDLVRSSQQLLKSVTNTLSNLQAGVVTPKRNKKV---DQNRIR--- 505
            ...:.:...|||.||.|     :..:.||.|......|:..:.|.:....:..   ..:::|   
Mouse   270 TLRQNRIPMEPPRTSQS-----LPPALQLQKEADAEPSSRPSAVFSSDPTEAPCGHSHSQVRRAG 329

  Fly   506 --SKPIPEQCL--------------------------------------------RQWACELAIA 524
              |.|.|.|.|                                            :|||.|:.:|
Mouse   330 QSSNPAPTQRLHWVREGADRVLGAYGRGRGRNPPSANRASLGSGRAAWSLREGQVKQWAAEMLLA 394

  Fly   525 IHSLHGKGVILRDLHMGNILLG-AKGQLLLTYFYQNEGLTSDDNYVHKALNLEAVANHFVAPE-- 586
            :.:||.:||:.|||:..|:||. |:|.:.||||    |..|:   |....:.|||...:.|||  
Mouse   395 LEALHQQGVLCRDLNPQNLLLDQAEGHIQLTYF----GQWSE---VEPRCSQEAVDCLYSAPEVG 452

  Fly   587 --RPLTFRSDWWSYGVVLYQLLLGVPYKVTHPGQLDLYGCVQYPSESLEISDHAKDLLEQLLQLS 649
              ..||...||||||.:||:||.|:....:||.....:..:|.|.   .:|..|..||.:|||..
Mouse   453 GISELTEACDWWSYGSLLYELLTGMALSQSHPSGFQAHTQLQLPE---WLSHPAASLLTELLQFE 514

  Fly   650 PELRL-----DYDQLQAHPFFKGIDWQAVL 674
            |:.||     ...:|::||||..|.|..::
Mouse   515 PQRRLGAGGGGTSRLKSHPFFSTIQWSRLM 544

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7156NP_650697.1 PX_SNX15_like 8..124 CDD:132791
MIT_SNX15 241..315 CDD:239140 30/73 (41%)
Protein Kinases, catalytic domain 343..665 CDD:473864 118/409 (29%)
Rps6kl1NP_001351244.1 MIT_SNX15 48..122 CDD:239140 32/88 (36%)
STKc_RPK118_like 148..535 CDD:270728 118/410 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 262..344 20/86 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 353..372 0/18 (0%)
Blue background indicates that the domain is not in the aligned region.

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