DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7156 and SNX20

DIOPT Version :9

Sequence 1:	NP_650697.1	Gene:	CG7156 / 42187	FlyBaseID:	FBgn0038588	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_878274.1	Gene:	SNX20 / 124460	HGNCID:	30390	Length:	316	Species:	Homo sapiens

Alignment Length:	279	Identity:	56/279 - (20%)
Similarity:	76/279 - (27%)	Gaps:	125/279 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 FD--AAVIQRRKEYILQLLDFAAQHPALYKCSTFTQFFQETPSP----NGSPLKKLYVERSLRLQ 144
            ||  .||::||..      |||....||.|  ||.:..::...|    .|:..:::..||...||
Human   106 FDNNKAVLERRYS------DFAKLQKALLK--TFREEIEDVEFPRKHLTGNFAEEMICERRRALQ 162

  Fly   145 ---------------------------TEDNGCGSGGSE-----------------TGTC-AGAI 164
                                       .|..||...|..                 |..| |.|:
Human   163 EYLGLLYAIRCVRRSREFLDFLTRPELREAFGCLRAGQYPRALELLLRVLPLQEKLTAHCPAAAV 227

  Fly   165 ADIC------DKLDLPYDPHDAGGITPLDPRCDKEQTNNESQAKETEIELETKQEPKTDVALTKR 223
            ..:|      ..||.|.:...||           |:.....||:|..                 |
Human   228 PALCAVLLCHRDLDRPAEAFAAG-----------ERALQRLQAREGH-----------------R 264

  Fly   224 DYLRLLTPMASIESDDSDYIYEAALEFSHAVQAEVNLEYAEAHERYKHGVDLLLNGAKQDSSEER 288
            .|..||..|                         |.|.||       .|.|.:....:.:.|:.|
Human   265 YYAPLLDAM-------------------------VRLAYA-------LGKDFVTLQERLEESQLR 297

  Fly   289 RFIAKAKIAKYLARAEEIH 307
            |...:....|.|...|.:|
Human   298 RPTPRGITLKELTVREYLH 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7156	NP_650697.1	PX_SNX15_like	8..124	CDD:132791	14/39 (36%)
		MIT_SNX15	241..315	CDD:239140	13/67 (19%)
		PKc_like	343..665	CDD:304357
SNX20	NP_878274.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..54
SNX20	NP_878274.1	PX_SNX20	76..189	CDD:132833	20/90 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810