DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7156 and Rps6ka2

DIOPT Version :9

Sequence 1:	NP_650697.1	Gene:	CG7156 / 42187	FlyBaseID:	FBgn0038588	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	XP_038934903.1	Gene:	Rps6ka2 / 117269	RGDID:	620676	Length:	762	Species:	Rattus norvegicus

Alignment Length:	355	Identity:	84/355 - (23%)
Similarity:	142/355 - (40%)	Gaps:	117/355 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   345 ARYKVLQIL----QDRVMQVQCVTKSQQPAAIMKGVEKPAS--------HSLTQSIFLPQQVPYM 397
            :::::|::|    ..:|..|:.||.|.........|.|.|:        ..:.:.|......|::
  Rat    86 SQFELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFI 150

  Fly   398 VQLLAYFQSEQKIFLLLRQAEGGMLYDYLQSYTPTSSKSVNYGELFPSDQEPEEKEAEEPPLTSD 462
            |:|...||:|.|::|:|         |:|:.           |:||
  Rat   151 VKLHYAFQTEGKLYLIL---------DFLRG-----------GDLF------------------- 176

  Fly   463 SDVSDLVRSSQQLLKSVTNTLSNLQAGVVTPKRNKKVDQNRIRSKPIPEQCLRQWACELAIAIHS 527
                  .|.|::::                                ..|:.::.:..|||:|:..
  Rat   177 ------TRLSKEVM--------------------------------FTEEDVKFYLAELALALDH 203

  Fly   528 LHGKGVILRDLHMGNILLGAKGQLLLTYF-YQNEGLTSDDNYVHKALNLEAVANHFVAPE----R 587
            |||.|:|.|||...||||..:|.:.:|.| ...|.:..|.........:|     ::|||    |
  Rat   204 LHGLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIE-----YMAPEVVNRR 263

  Fly   588 PLTFRSDWWSYGVVLYQLLLG-VPY-----KVTHPGQLDL-YGCVQYPSESLEISDHAKDLLEQL 645
            ..|..:||||:||:::::|.| :|:     |.|....|.. .|..|:      :|..|:.||..|
  Rat   264 GHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQF------LSAEAQSLLRAL 322

  Fly   646 LQLSPELRL-----DYDQLQAHPFFKGIDW 670
            .:.:|..||     ..::::.||||..|||
  Rat   323 FKRNPCNRLGAGVDGVEEIKRHPFFVTIDW 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7156	NP_650697.1	PX_SNX15_like	8..124	CDD:132791
		MIT_SNX15	241..315	CDD:239140
		PKc_like	343..665	CDD:304357	79/348 (23%)
Rps6ka2	XP_038934903.1	STKc_RSK_N	92..408	CDD:270734	83/349 (24%)
Rps6ka2	XP_038934903.1	STKc_RSK3_C	440..732	CDD:271080
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0603
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900