DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7156 and rps6kl1

DIOPT Version :9

Sequence 1:	NP_650697.1	Gene:	CG7156 / 42187	FlyBaseID:	FBgn0038588	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	XP_031747280.1	Gene:	rps6kl1 / 100492018	XenbaseID:	XB-GENE-991864	Length:	464	Species:	Xenopus tropicalis

Alignment Length:	528	Identity:	150/528 - (28%)
Similarity:	233/528 - (44%)	Gaps:	105/528 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 ITPLD---------PRCDKEQTNNESQAKETEIELETKQEPKTDVALTKRDYLRLLTPMASIESD 238
            :||.|         ..|.:.:.:|:.:...|.: :|....|||   |:|||||
Frog     6 MTPTDCSFYGPFVLAMCSEGELSNQYRVGFTGV-VEQTSGPKT---LSKRDYL------------ 54

  Fly   239 DSDYIYEAALEFSHAVQAEVNLEYAEAHERYKHGVDLLLNGAKQDSSEERRFIAKAKIAKYLARA 303
                 .:||.:...|::.:||.||..|...|||||:|||:|...|.|.|||...|.||::||.||
Frog    55 -----VDAAKQLHVALERDVNEEYEAAFSHYKHGVELLLSGVTVDPSRERRDAVKRKISQYLKRA 114

  Fly   304 EEIHANFL----ANDCPTKKLQFQLSLDTTDGGS------VSHLECPWNQLARYKVLQILQDRVM 358
            |||....|    .|.|           ..|:|.|      :..|......|...|:|:|    :.
Frog   115 EEIFNCHLQRPVGNVC-----------GATEGYSSLRFRPIRALSAAVENLKNCKILKI----IG 164

  Fly   359 QVQCV----TKSQQPAAIMKGVEKPASHSLTQSIFLPQQVPYMVQLLAYFQSEQKIFLLLRQAEG 419
            :||.|    |:|   ..::|.:.|...........:||.||:||||..::.|:..:.|.|:...|
Frog   165 KVQLVHDPCTES---TFVLKSLMKSGRSGHGTVTIIPQCVPFMVQLQRFYVSDDSLHLQLQYIPG 226

  Fly   420 GMLYDYLQSYTPTSSKSVNYGELFPSDQEPEEKEAEEPPLTSDSDVSDLVRSSQQLLKSVTNTLS 484
            |.|:..|:.| .|.|:|:::            ::....|.:|...|.......|.|...:.:..|
Frog   227 GCLWGQLRKY-QTKSQSIDF------------QQTNILPTSSPKQVLGPENDCQPLATFIHSPPS 278

  Fly   485 NLQAGVVTPKRNKKVDQNRIRSKP---IPEQCLRQWACELAIAIHSLHGKGVILRDLHMGNILLG 546
            :| ..:..|.     :.:.:.|:|   |.|..:|.|..:|.:|:.:||.:||:.|||:..|:||.
Frog   279 HL-TELCDPS-----NSSGLCSEPVGCILESQVRLWGAQLILALETLHQEGVLCRDLNPRNLLLD 337

  Fly   547 AKGQLLLTYFYQ-NEGLTSDDNYVHKALNLEAVANHFVAPE----RPLTFRSDWWSYGVVLYQLL 606
            ..|.:.||||.| .|        |......:|....:||||    ..:....||||.||:||::|
Frog   338 DSGDVYLTYFGQWRE--------VEITYCPDAAERLYVAPEVLGVGTVNEACDWWSLGVLLYEML 394

  Fly   607 LGVPYKVTHPGQLDLYGCVQYPSESLEISDHAKDLLEQLLQLSPELRL-----DYDQLQAHPFFK 666
            .|.....:....::.:..|.:|:   .::..|..||.:||...|..||     ...:::.||||.
Frog   395 TGQSLYDSLTSGVNAHMQVPFPN---TLTSAAISLLTELLCYDPGKRLGSGPGGAQKIKTHPFFY 456

  Fly   667 GIDWQAVL 674
            |:.|..::
Frog   457 GVQWNKLV 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7156	NP_650697.1	PX_SNX15_like	8..124	CDD:132791
		MIT_SNX15	241..315	CDD:239140	34/77 (44%)
		PKc_like	343..665	CDD:304357	91/338 (27%)
rps6kl1	XP_031747280.1	MIT_SNX15	52..125	CDD:239140	36/89 (40%)
rps6kl1	XP_031747280.1	PKc_like	152..455	CDD:419665	91/339 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I6905
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D135297at33208
OrthoFinder	1	1.000	-	-		FOG0007114
OrthoInspector	1	1.000	-	-		otm49287
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3828
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.040