DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 14-3-3epsilon and ywhaba

DIOPT Version :9

Sequence 1:	NP_732309.1	Gene:	14-3-3epsilon / 42186	FlyBaseID:	FBgn0020238	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001076267.1	Gene:	ywhaba / 323055	ZFINID:	ZDB-GENE-030131-6583	Length:	244	Species:	Danio rerio

Alignment Length:	246	Identity:	160/246 - (65%)
Similarity:	201/246 - (81%)	Gaps:	4/246 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ERENNVYKAKLAEQAERYDEMVEAMKKVASMDVELTVEERNLLSVAYKNVIGARRASWRIITSIE 67
            ::.:.|.||||||||||||:|..:||.|....|||:.|||||||||||||:||||:|||:|:|||
Zfish     2 DKSDLVQKAKLAEQAERYDDMAASMKAVTEGGVELSNEERNLLSVAYKNVVGARRSSWRVISSIE 66

  Fly    68 QKEENKGAEEKLEMIKTYRGQVEKELRDICSDILNVLEKHLIPCATSGESKVFYYKMKGDYHRYL 132
            ||.|  |.|:|.:|.:.||.::|.||::||:|:|.:|||:|||.|:..||||||.||||||:|||
Zfish    67 QKTE--GNEKKQQMAREYREKIEAELQEICNDVLGLLEKYLIPNASQAESKVFYLKMKGDYYRYL 129

  Fly   133 AEFATGSDRKDAAENSLIAYKAASDIAMNDLPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKA 197
            :|.|:|..::...|||..||:.|.:|:..::.||||||||||||||||||||||:|::||.|||.
Zfish   130 SEVASGDSKRTTVENSQKAYQDAFEISKKEMQPTHPIRLGLALNFSVFYYEILNTPEQACSLAKT 194

  Fly   198 AFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQAEEVDPNAGDGE 248
            |||:||||||||:|:|||||||||||||||||||||:.|.:|.|  ||:||
Zfish   195 AFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSENQGDEGD--AGEGE 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
14-3-3epsilon	NP_732309.1	14-3-3_epsilon	4..233	CDD:206757	151/228 (66%)
ywhaba	NP_001076267.1	14-3-3_beta_zeta	2..230	CDD:206758	151/229 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5040
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53683
OrthoDB	1	1.010	-	-		D1176818at2759
OrthoFinder	1	1.000	-	-		FOG0000128
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100283
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1059
SonicParanoid	1	1.000	-	-		X206
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.760