DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 14-3-3epsilon and Ywhah

DIOPT Version :9

Sequence 1:	NP_732309.1	Gene:	14-3-3epsilon / 42186	FlyBaseID:	FBgn0020238	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_037184.1	Gene:	Ywhah / 25576	RGDID:	3978	Length:	246	Species:	Rattus norvegicus

Alignment Length:	249	Identity:	157/249 - (63%)
Similarity:	191/249 - (76%)	Gaps:	6/249 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTERENNVYKAKLAEQAERYDEMVEAMKKVASMDVELTVEERNLLSVAYKNVIGARRASWRIITS 65
            |.:||..:.:|:|||||||||:|..|||.|..::..|:.|:|||||||||||:||||:|||:|:|
  Rat     1 MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSWRVISS 65

  Fly    66 IEQKEENKGAEEKLEMIKTYRGQVEKELRDICSDILNVLEKHLIPCAT--SGESKVFYYKMKGDY 128
            ||||....|.|:|||.:|.||.::||||..:|:|:|.:|:|.||....  ..||||||.||||||
  Rat    66 IEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLALLDKFLIKNCNDFQYESKVFYLKMKGDY 130

  Fly   129 HRYLAEFATGSDRKDAAENSLIAYKAASDIAMNDLPPTHPIRLGLALNFSVFYYEILNSPDRACR 193
            :|||||.|:|..:....|.|..|||.|.:|:...:.||||||||||||||||||||.|:|::||.
  Rat   131 YRYLAEVASGEKKNSVVEASEAAYKEAFEISKEHMQPTHPIRLGLALNFSVFYYEIQNAPEQACL 195

  Fly   194 LAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQAEEVDPNAGDG 247
            |||.||||||||||||:|:||||||||||||||||||||||.|.||    ||:|
  Rat   196 LAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDEE----AGEG 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
14-3-3epsilon	NP_732309.1	14-3-3_epsilon	4..233	CDD:206757	147/230 (64%)
Ywhah	NP_037184.1	14-3-3_eta	3..241	CDD:206761	151/237 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53683
OrthoDB	1	1.010	-	-		D1176818at2759
OrthoFinder	1	1.000	-	-		FOG0000128
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930