DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 14-3-3epsilon and par-5

DIOPT Version :9

Sequence 1:	NP_732309.1	Gene:	14-3-3epsilon / 42186	FlyBaseID:	FBgn0020238	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001369936.1	Gene:	par-5 / 178113	WormBaseID:	WBGene00003920	Length:	248	Species:	Caenorhabditis elegans

Alignment Length:	235	Identity:	160/235 - (68%)
Similarity:	190/235 - (80%)	Gaps:	3/235 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ENNVYKAKLAEQAERYDEMVEAMKKVASMDVELTVEERNLLSVAYKNVIGARRASWRIITSIEQK 69
            |..|.:|||||||||||:|..|||||.....||:.|||||||||||||:||||:|||:|:|||||
Worm     6 EELVQRAKLAEQAERYDDMAAAMKKVTEQGQELSNEERNLLSVAYKNVVGARRSSWRVISSIEQK 70

  Fly    70 EENKGAEEKLEMIKTYRGQVEKELRDICSDILNVLEKHLIPCATSGESKVFYYKMKGDYHRYLAE 134
            .|  |:|:|.::.|.||.:||:||.|||.|:|.:|::.||..|.:.||||||.||||||:|||||
Worm    71 TE--GSEKKQQLAKEYRVKVEQELNDICQDVLKLLDEFLIVKAGAAESKVFYLKMKGDYYRYLAE 133

  Fly   135 FATGSDRKDAAENSLIAYKAASDIAMNDLPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAF 199
            .|: .||....|.|..||:.|.|||.:.:.||||||||||||||||||||||:|:.||:|||.||
Worm   134 VAS-EDRAAVVEKSQKAYQEALDIAKDKMQPTHPIRLGLALNFSVFYYEILNTPEHACQLAKQAF 197

  Fly   200 DDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQAEE 239
            ||||||||||:|:||||||||||||||||||||||:.||:
Worm   198 DDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDVGAED 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
14-3-3epsilon	NP_732309.1	14-3-3_epsilon	4..233	CDD:206757	155/227 (68%)
par-5	NP_001369936.1	14-3-3	6..232	CDD:413191	156/228 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53683
OrthoDB	1	1.010	-	-		D1176818at2759
OrthoFinder	1	1.000	-	-		FOG0000128
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100283
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1059
SonicParanoid	1	1.000	-	-		X206
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.860