Protein Alignment Mdh2 and mdh

DIOPT Version :10

• Sequence 1: NP_650696.1
• Gene: Mdh2 / 42185
• FlyBaseID: FBgn0262559
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_417703.1
• Gene: mdh / 947854
• ECOCYCID: EG10576
• Length: 312
• Species: Escherichia coli
• Alignment Length: 312
• Identity: 180/312 - (57%)
• Similarity: 221/312 - (70%)
• Gaps: 4/312 - (1%)

  Fly    26 KVTVCGAAGGIGQPLSLLLK-QNPLVTDLALYDIVH-TPGVAADLSHIDTKSKTAGFIGADQLGD 88
            ||.|.||||||||.|:|||| |.|..::|:||||.. |||||.|||||.|..|..||.|.|.. .
E. coli     2 KVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGEDAT-P 65

  Fly    89 SLKGSDVVVIPAGVPRKPGMTRDDLFNVNAGIIKDISNSIAKNCPKALVAIITNPVNTCVPIAAE 153
            :|:|:|||:|.|||.|||||.|.|||||||||:|::...:||.||||.:.||||||||.|.||||
E. coli    66 ALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAKTCPKACIGIITNPVNTTVAIAAE 130

  Fly   154 ILKKAGVYDPKRLFGVSTLDVVRARAFIGHALGVDPQTVQIPVIGGHSGVTILPVLSQSQPLFKG 218
            :||||||||..:||||:|||::|:..|:....|..|..|::|||||||||||||:||| .|....
E. coli   131 VLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKQPGEVEVPVIGGHSGVTILPLLSQ-VPGVSF 194

  Fly   219 NQDTIEKLTVRIQEAGTEVVKAKAGAGSATLSMAYAGARFAGSLLKGLNGEKNVIECSYVQSTVT 283
            .:..:..||.|||.||||||:||||.|||||||..|.|||..||::.|.||:.|:||:||:....
E. coli   195 TEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQ 259

  Fly   284 EATFFSTPLVLGKNGVQENLGLPKLNDYEKKLLEAAIPELKKNIQKGIDFAN 335
            .|.|||.||:||||||:|...:..|:.:|:..||..:..|||:|..|.:|.|
E. coli   260 YARFFSQPLLLGKNGVEERKSIGTLSAFEQNALEGMLDTLKKDIALGEEFVN 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdh2	NP_650696.1	MDH_glyoxysomal_mitochondrial	25..334	CDD:133422	178/309 (58%)
mdh	NP_417703.1	MDH_glyoxysomal_mitochondrial	1..310	CDD:133422	178/309 (58%)