Protein Alignment Mdh2 and MDH1

DIOPT Version :10

• Sequence 1: NP_650696.1
• Gene: Mdh2 / 42185
• FlyBaseID: FBgn0262559
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_012838.1
• Gene: MDH1 / 853777
• SGDID: S000001568
• Length: 334
• Species: Saccharomyces cerevisiae
• Alignment Length: 338
• Identity: 172/338 - (50%)
• Similarity: 233/338 - (68%)
• Gaps: 13/338 - (3%)

  Fly     1 MLKQVTKQLALQGVRTFSVGQQNNYKVTVCGAAGGIGQPLSLLLKQNPLVTDLALYDIVHTPGVA 65
            ||.:|.|       |.||....|.|||||.||.||||||||||||.|..||||.|||:....|||
Yeast     1 MLSRVAK-------RAFSSTVANPYKVTVLGAGGGIGQPLSLLLKLNHKVTDLRLYDLKGAKGVA 58

  Fly    66 ADLSHIDTKSKTAGFI--GADQLGDSLKGSDVVVIPAGVPRKPGMTRDDLFNVNAGIIKDISNSI 128
            .|||||.|.|...||.  ..|.|.::||.:|:|:|||||||||||||||||.:||.|::|::.:.
Yeast    59 TDLSHIPTNSVVKGFTPEEPDGLNNALKDTDMVLIPAGVPRKPGMTRDDLFAINASIVRDLAAAT 123

  Fly   129 AKNCPKALVAIITNPVNTCVPIAAEILKKAGVYDPKRLFGVSTLDVVRARAFIGHALGVDPQTVQ 193
            |::.|.|.:.:|:||||:.|||.|::||..|||:||:||||:|||.:||..||......||...:
Yeast   124 AESAPNAAILVISNPVNSTVPIVAQVLKNKGVYNPKKLFGVTTLDSIRAARFISEVENTDPTQER 188

  Fly   194 IPVIGGHSGVTILPVLSQSQPLFKGNQDTIEKLTVRIQEAGTEVVKAKAGAGSATLSMAYAGARF 258
            :.|||||||:||:|::||:..... :.|...:|..|||..|.||||||.||||||||||:|||:|
Yeast   189 VNVIGGHSGITIIPLISQTNHKLM-SDDKRHELIHRIQFGGDEVVKAKNGAGSATLSMAHAGAKF 252

  Fly   259 AGSLLKGLNGEKNVIECSYVQSTVTEA---TFFSTPLVLGKNGVQENLGLPKLNDYEKKLLEAAI 320
            |.::|.|..||::|||.|:|.|.:.::   .||::|:.||.:|:::...:.:|:..|:::|:...
Yeast   253 ANAVLSGFKGERDVIEPSFVDSPLFKSEGIEFFASPVTLGPDGIEKIHPIGELSSEEEEMLQKCK 317

  Fly   321 PELKKNIQKGIDF 333
            ..|||||:||::|
Yeast   318 ETLKKNIEKGVNF 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdh2	NP_650696.1	MDH_glyoxysomal_mitochondrial	25..334	CDD:133422	164/314 (52%)
MDH1	NP_012838.1	MDH_glyoxysomal_mitochondrial	18..331	CDD:133422	164/314 (52%)