Protein Alignment Mdh2 and MDH3

DIOPT Version :10

• Sequence 1: NP_650696.1
• Gene: Mdh2 / 42185
• FlyBaseID: FBgn0262559
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_010205.1
• Gene: MDH3 / 851481
• SGDID: S000002236
• Length: 343
• Species: Saccharomyces cerevisiae
• Alignment Length: 337
• Identity: 149/337 - (44%)
• Similarity: 213/337 - (63%)
• Gaps: 32/337 - (9%)

  Fly    26 KVTVCGAAGGIGQPLSLLLKQNPLVTDLALYDIVHTPGVAADLSHIDTKSKTAGFIGADQLGDSL 90
            ||.:.||:||:|||||||||.:|.|::||||||....|:..|||||:|.|...|: ..|.:.::|
Yeast     3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGY-DKDSIENTL 66

  Fly    91 KGSDVVVIPAGVPRKPGMTRDDLFNVNAGIIKDISNSIAKNCPKALVAIITNPVNTCVPIAAEIL 155
            ..:.||:||||||||||:||||||.:||||:|.:..::.|..|.|.:.:|:||||:.||||.|.|
Yeast    67 SNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETL 131

  Fly   156 KKAGVYDPKRLFGVSTLDVVRARAFIGHALGV---------DPQTV--QIPVIGGHSGVTILPVL 209
            ||.|.:.|..:.||:.||:|||..|:...|.:         |..|:  ::.|||||||.||:|::
Yeast   132 KKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGETIIPII 196

  Fly   210 SQSQPLFKGNQDTIEKLTVRIQEAGTEVVKAKAGAGSATLSMAYAGARFAGSLLKGLNGEKNVIE 274
            :....:|:.::. .|....|:|..|.|:||||.||||||||||:|||:||..:|:..:.||...|
Yeast   197 TDKSLVFQLDKQ-YEHFIHRVQFGGDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETE 260

  Fly   275 --CSYV-----------QSTVTEAT--FFSTPLVLGKNGVQENLG---LPKLNDYEKKLLEAAIP 321
              .::|           |..|.:.:  :||.|:|| :||...::.   |.||:..|::|:..|:.
Yeast   261 SLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVL-RNGSVVSIDTSVLEKLSPREEQLVNTAVK 324

  Fly   322 ELKKNIQKGIDF 333
            ||:|||:||..|
Yeast   325 ELRKNIEKGKSF 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdh2	NP_650696.1	MDH_glyoxysomal_mitochondrial	25..334	CDD:133422	149/337 (44%)
MDH3	NP_010205.1	MDH_euk_gproteo	3..339	CDD:130833	149/337 (44%)