DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mdh2 and MDH

DIOPT Version :9

Sequence 1:	NP_650696.1	Gene:	Mdh2 / 42185	FlyBaseID:	FBgn0262559	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_190336.1	Gene:	MDH / 823906	AraportID:	AT3G47520	Length:	403	Species:	Arabidopsis thaliana

Alignment Length:	314	Identity:	186/314 - (59%)
Similarity:	238/314 - (75%)	Gaps:	2/314 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 NYKVTVCGAAGGIGQPLSLLLKQNPLVTDLALYDIVHTPGVAADLSHIDTKSKTAGFIGADQLGD 88
            :|||.|.|||||||||||||:|.:|||:.|.||||.:..||||||||.:|.|:...|.|..:|.|
plant    82 SYKVAVLGAAGGIGQPLSLLIKMSPLVSTLHLYDIANVKGVAADLSHCNTPSQVRDFTGPSELAD 146

  Fly    89 SLKGSDVVVIPAGVPRKPGMTRDDLFNVNAGIIKDISNSIAKNCPKALVAIITNPVNTCVPIAAE 153
            .||..:|||||||||||||||||||||:||.|:|.:..::|:|||.|.:.||:||||:.||||||
plant   147 CLKDVNVVVIPAGVPRKPGMTRDDLFNINANIVKTLVEAVAENCPNAFIHIISNPVNSTVPIAAE 211

  Fly   154 ILKKAGVYDPKRLFGVSTLDVVRARAFIGHALGVDPQTVQIPVIGGHSGVTILPVLSQSQPLFKG 218
            :|||.||||||:||||:|||||||..|:.....:....|.:||||||:|:||||:||:::|....
plant   212 VLKKKGVYDPKKLFGVTTLDVVRANTFVSQKKNLKLIDVDVPVIGGHAGITILPLLSKTKPSVNF 276

  Fly   219 NQDTIEKLTVRIQEAGTEVVKAKAGAGSATLSMAYAGARFAGSLLKGLNGEKNVIECSYVQSTVT 283
            ..:.|::||||||.||||||.|||||||||||||||.|||..|.|:.|:|:.:|.|||:|:||:|
plant   277 TDEEIQELTVRIQNAGTEVVDAKAGAGSATLSMAYAAARFVESSLRALDGDGDVYECSFVESTLT 341

  Fly   284 EATFFSTPLVLGKNGVQENL--GLPKLNDYEKKLLEAAIPELKKNIQKGIDFAN 335
            :..||::.:.:||||::..:  .|..|.:||:|.|||...|||.:|.||:.|||
plant   342 DLPFFASRVKIGKNGLEAVIESDLQGLTEYEQKALEALKVELKASIDKGVAFAN 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mdh2	NP_650696.1	MDH_glyoxysomal_mitochondrial	25..334	CDD:133422	183/310 (59%)
MDH	NP_190336.1	PLN00106	80..389	CDD:215058	181/306 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	185	1.000	Domainoid score	I994
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56560
OrthoDB	1	1.010	-	-		D976445at2759
OrthoFinder	1	1.000	-	-		FOG0001716
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101212
Panther	1	1.100	-	-	O	PTHR11540
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1106
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.790