DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mdh2 and mMDH2

DIOPT Version :9

Sequence 1:	NP_650696.1	Gene:	Mdh2 / 42185	FlyBaseID:	FBgn0262559	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_188120.1	Gene:	mMDH2 / 820731	AraportID:	AT3G15020	Length:	341	Species:	Arabidopsis thaliana

Alignment Length:	326	Identity:	202/326 - (61%)
Similarity:	256/326 - (78%)	Gaps:	2/326 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 QGV--RTFSVGQQNNYKVTVCGAAGGIGQPLSLLLKQNPLVTDLALYDIVHTPGVAADLSHIDTK 74
            ||:  |.|:.....:.||.:.|||||||||||||:|.||||:.|:||||.:|||||||:.||:|:
plant    15 QGLLRRGFASESVPDRKVVILGAAGGIGQPLSLLMKLNPLVSSLSLYDIANTPGVAADVGHINTR 79

  Fly    75 SKTAGFIGADQLGDSLKGSDVVVIPAGVPRKPGMTRDDLFNVNAGIIKDISNSIAKNCPKALVAI 139
            |:.:|::|.|.||.:|:|:|:|:||||||||||||||||||:||||:|::|.:|||.||:|||.:
plant    80 SQVSGYMGDDDLGKALEGADLVIIPAGVPRKPGMTRDDLFNINAGIVKNLSIAIAKYCPQALVNM 144

  Fly   140 ITNPVNTCVPIAAEILKKAGVYDPKRLFGVSTLDVVRARAFIGHALGVDPQTVQIPVIGGHSGVT 204
            |:||||:.|||||||.||||.||.|:||||:||||||||.|......|:...|.:||:|||:|:|
plant   145 ISNPVNSTVPIAAEIFKKAGTYDEKKLFGVTTLDVVRARTFYAGKSDVNVAEVNVPVVGGHAGIT 209

  Fly   205 ILPVLSQSQPLFKGNQDTIEKLTVRIQEAGTEVVKAKAGAGSATLSMAYAGARFAGSLLKGLNGE 269
            |||:.||:.|....:.|.|..||.|.|:.|||||:||||.||||||||||||.||.:.||||||.
plant   210 ILPLFSQASPQANLSDDLIRALTKRTQDGGTEVVEAKAGKGSATLSMAYAGALFADACLKGLNGV 274

  Fly   270 KNVIECSYVQSTVTEATFFSTPLVLGKNGVQENLGLPKLNDYEKKLLEAAIPELKKNIQKGIDFA 334
            .||:|||:||||:||..||::.:.||||||:|.|.|..|:|:||:.|||...|||.:|:|||.||
plant   275 PNVVECSFVQSTITELPFFASKVRLGKNGVEEVLDLGPLSDFEKEGLEALKAELKSSIEKGIKFA 339

  Fly   335 N 335
            |
plant   340 N 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mdh2	NP_650696.1	MDH_glyoxysomal_mitochondrial	25..334	CDD:133422	195/308 (63%)
mMDH2	NP_188120.1	PLN00106	14..334	CDD:215058	196/318 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	211	1.000	Domainoid score	I789
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55938
Inparanoid	1	1.050	397	1.000	Inparanoid score	I477
OMA	1	1.010	-	-		QHG56560
OrthoDB	1	1.010	-	-		D976445at2759
OrthoFinder	1	1.000	-	-		FOG0001716
OrthoInspector	1	1.000	-	-		otm3098
orthoMCL	1	0.900	-	-		OOG6_101212
Panther	1	1.100	-	-	O	PTHR11540
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1106
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840