DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mdh2 and PMDH1

DIOPT Version :9

Sequence 1:	NP_650696.1	Gene:	Mdh2 / 42185	FlyBaseID:	FBgn0262559	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_179863.1	Gene:	PMDH1 / 816808	AraportID:	AT2G22780	Length:	354	Species:	Arabidopsis thaliana

Alignment Length:	331	Identity:	187/331 - (56%)
Similarity:	243/331 - (73%)	Gaps:	0/331 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QVTKQLALQGVRTFSVGQQNNYKVTVCGAAGGIGQPLSLLLKQNPLVTDLALYDIVHTPGVAADL 68
            |:.....|..|...:.|....:||.:.||||||||||::|:|.||||:.|.|||:.:.|||.||:
plant    22 QIADGSGLNRVACRAKGGSPGFKVAILGAAGGIGQPLAMLMKMNPLVSVLHLYDVANAPGVTADI 86

  Fly    69 SHIDTKSKTAGFIGADQLGDSLKGSDVVVIPAGVPRKPGMTRDDLFNVNAGIIKDISNSIAKNCP 133
            ||:||.:...||:|..||.::|.|.|:|:||||||||||||||||||:||||::.:|.:|||.||
plant    87 SHMDTSAVVRGFLGQPQLEEALTGMDLVIIPAGVPRKPGMTRDDLFNINAGIVRTLSEAIAKCCP 151

  Fly   134 KALVAIITNPVNTCVPIAAEILKKAGVYDPKRLFGVSTLDVVRARAFIGHALGVDPQTVQIPVIG 198
            ||:|.||:||||:.||||||:.||||.:|||:|.||:.||||||..|:...:.:||:.|::||:|
plant   152 KAIVNIISNPVNSTVPIAAEVFKKAGTFDPKKLMGVTMLDVVRANTFVAEVMSLDPREVEVPVVG 216

  Fly   199 GHSGVTILPVLSQSQPLFKGNQDTIEKLTVRIQEAGTEVVKAKAGAGSATLSMAYAGARFAGSLL 263
            ||:||||||:|||.:|.....|..||.||.|||..|||||:|||||||||||||||...||.:.|
plant   217 GHAGVTILPLLSQVKPPCSFTQKEIEYLTDRIQNGGTEVVEAKAGAGSATLSMAYAAVEFADACL 281

  Fly   264 KGLNGEKNVIECSYVQSTVTEATFFSTPLVLGKNGVQENLGLPKLNDYEKKLLEAAIPELKKNIQ 328
            :||.|:.|::||:||.|.|||..||::.:.||:.|:.|..||..||:||:..||.|..||..:|.
plant   282 RGLRGDANIVECAYVASHVTELPFFASKVRLGRCGIDEVYGLGPLNEYERMGLEKAKKELSVSIH 346

  Fly   329 KGIDFA 334
            ||:.||
plant   347 KGVTFA 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mdh2	NP_650696.1	MDH_glyoxysomal_mitochondrial	25..334	CDD:133422	181/308 (59%)
PMDH1	NP_179863.1	PLN00106	33..347	CDD:215058	180/313 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	211	1.000	Domainoid score	I789
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	397	1.000	Inparanoid score	I477
OMA	1	1.010	-	-		QHG56560
OrthoDB	1	1.010	-	-		D976445at2759
OrthoFinder	1	1.000	-	-		FOG0001716
OrthoInspector	1	1.000	-	-		otm3098
orthoMCL	1	0.900	-	-		OOG6_101212
Panther	1	1.100	-	-	LDO	PTHR11540
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1106
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840