Protein Alignment Mdh2 and Uevld

DIOPT Version :9

• Sequence 1: NP_650696.1
• Gene: Mdh2 / 42185
• FlyBaseID: FBgn0262559
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_001035785.1
• Gene: Uevld / 54122
• MGIID: 1860490
• Length: 471
• Species: Mus musculus
• Alignment Length: 345
• Identity: 71/345 - (20%)
• Similarity: 116/345 - (33%)
• Gaps: 103/345 - (29%)

  Fly     1 MLKQVTKQLALQGVRTFSVGQQNNY------KVTVCGAAGGIGQPLSLLLKQNPLVTDLAL---- 55
            :|..:||  ..:||...:.....|:      |:||.| :|.:|...:|.:....:...|.|
Mouse   155 LLAYITK--ITEGVSDINSRGWTNHENKILNKITVVG-SGDLGIACTLAISAKGIADKLLLLDLS 216

  Fly    56 ---------YDIVHTPGV--AADLSHIDTKSKTAGFIGADQLGDSLKGSDVVVIPAGVPRKPGMT 109
                     .||.:.|.|  :.||| ....||...|     ..:||.||:..:
Mouse   217 DGMSQGTMDLDIFNLPNVEISKDLS-ASAHSKVVIF-----TANSLGGSESYL------------ 263

  Fly   110 RDDLFNVNAGIIKDISNSIAKNCPKALVAIITNPVNTCVPIAAEILKKAGVYDPKRLFGVS-TLD 173
              .....|..:.:.:..::......|::.:.:.||.    |.:.:..|...:...|:.|:. .||
Mouse   264 --HAVQSNVDMFRALVPALGHYSQHAVLLVASQPVE----IMSYVTWKLSTFPATRVVGIGCNLD 322

  Fly   174 VVRARAFIGHALGVDPQTVQIPVIG-----------GHSGVTILPVLSQSQPLFKGNQDTIEKLT 227
            ..|.:..|...|.|.....::.|:|           |..||  |...||:|
Mouse   323 SQRLQYIITSVLKVQTSGKEVWVVGEQGENKVCSWSGRDGV--LSPSSQAQ-------------- 371

  Fly   228 VRIQEAGTEVVKAKAGAGSATLSMAYAG-----------ARFAGSLLKGLNGEKNVIECSYVQST 281
              :.....|::|.| |..|.::.::.|.           .....:|.||..|..|.:
Mouse   372 --LSSRAMELLKVK-GQRSWSVGLSVADLVDTIINNKRKVHSVSTLAKGYYGLDNEV-------- 425

  Fly   282 VTEATFFSTPLVLGKNGVQE 301
                 |.|.|.:||..||.|
Mouse   426 -----FLSLPCILGTGGVSE 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdh2	NP_650696.1	MDH_glyoxysomal_mitochondrial	25..334	CDD:133422	65/321 (20%)
Uevld	NP_001035785.1	UEV	21..138	CDD:283415
		PLN02602	177..471	CDD:178212	65/321 (20%)
		NADB_Rossmann	183..468	CDD:304358	65/315 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810