Protein Alignment Mdh2 and ldha

DIOPT Version :10

• Sequence 1: NP_650696.1
• Gene: Mdh2 / 42185
• FlyBaseID: FBgn0262559
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_571321.1
• Gene: ldha / 30496
• ZFINID: ZDB-GENE-991026-5
• Length: 333
• Species: Danio rerio
• Alignment Length: 329
• Identity: 98/329 - (29%)
• Similarity: 155/329 - (47%)
• Gaps: 47/329 - (14%)

  Fly    26 KVTVCGAA-GGIGQPLSLLLKQNPLVTDLALYDIVH--TPGVAADLSHIDTKSKTAGFIGADQLG 87
            ||||.|.. .|:...:|:|||.  |..:|||.|::.  ..|.|.||.|.....||...: ||:..
Zfish    23 KVTVVGVGMVGMAAAVSILLKD--LTDELALVDVMEDKLKGEAMDLQHGSLFLKTHKIV-ADKDY 84

  Fly    88 DSLKGSDVVVIPAGVPRKPGMTRDDLFNVNAGIIKDISNSIAKNCPKALVAIITNPVNTCVPIAA 152
            .....|.|||:.||..::.|.:|.:|...|..|.|.|..:|.|..|..::.:::|||:....:|
Zfish    85 SVTANSKVVVVTAGARQQEGESRLNLVQRNVNIFKFIIPNIIKYSPNCILLVVSNPVDILTYVA- 148

  Fly   153 EILKKAGVYDPK-RLFGVST-LDVVRARAFIGHALGVDPQTVQIPVIGGH--------SGVTI-- 205
              .|.:|:  |: |:.|..| ||..|.|..:|..||:.|.:....|:|.|        |||.:
Zfish   149 --WKLSGL--PRNRVIGSGTNLDSARFRYLMGEKLGIHPSSCHGWVVGEHGDSSVPVWSGVNVAG 209

  Fly   206 --LPVLSQSQPLFKGNQD--TIEKLTVRIQEAGTEVVKAKAGAGSATLSMAYAGARFAGSLLKGL 266
              |..|:......|..:|  ::.|:.|   ::..||:|.|   |..:.::..:.|....|:|
Zfish   210 VSLQALNPDLGTDKDKEDWKSVHKMVV---DSAYEVIKLK---GYTSWAIGMSVADLCESIL--- 265

  Fly   267 NGEKNVIECSYVQST------VTEATFFSTPLVLGKNGVQENLGLPKLNDYEKKLLEAAIPELKK 325
               ||:.:|..|.:.      |.|..|.|.|.:||.||:.:.:.:....:.||:|:::|  |...
Zfish   266 ---KNMHKCHPVSTLVKGMHGVNEEVFLSVPCILGNNGLTDVVHMTLKPEEEKQLVKSA--ETLW 325

  Fly   326 NIQK 329
            .:||
Zfish   326 GVQK 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdh2	NP_650696.1	MDH_glyoxysomal_mitochondrial	25..334	CDD:133422	98/329 (30%)
ldha	NP_571321.1	LDH_1	19..330	CDD:133429	98/329 (30%)