Protein Alignment Mdh2 and Ldhb

DIOPT Version :10

• Sequence 1: NP_650696.1
• Gene: Mdh2 / 42185
• FlyBaseID: FBgn0262559
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_001303262.1
• Gene: Ldhb / 24534
• RGDID: 2997
• Length: 341
• Species: Rattus norvegicus
• Alignment Length: 342
• Identity: 87/342 - (25%)
• Similarity: 145/342 - (42%)
• Gaps: 65/342 - (19%)

  Fly    24 NYKVTVCGAAGGIGQPLSLLLKQNPLVTDLALYDIVH--TPGVAADLSHIDTKSKTAGFIGADQL 86
            |.|:||.| .|.:|...::.:....|..:|||.|::.  ..|...||.|.....:|...: ||:.
  Rat    21 NNKITVVG-VGQVGMACAISILGKSLADELALVDVLEDKLKGEMMDLQHGSLFLQTPKIV-ADKD 83

  Fly    87 GDSLKGSDVVVIPAGVPRKPGMTRDDLFNVNAGIIKDISNSIAKNCPKALVAIITNPVNTCVPIA 151
            ......|.:||:.|||.::.|.:|.:|...|..:.|.|...|.|..|...:.:::|||:....:.
  Rat    84 YSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCTIIVVSNPVDILTYVT 148

  Fly   152 AEILKKAGVYDPK-RLFGVS-TLDVVRARAFIGHALGVDPQTVQIPVIGGH--------SGVTIL 206
               .|.:|:  || |:.|.. .||..|.|..:...||:.|.:....::|.|        |||.:.
  Rat   149 ---WKLSGL--PKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSVAVWSGVNVA 208

  Fly   207 PV-LSQSQPLFKGNQDT-----IEKLTVRIQEAGTEVVKAKA------GAGSATL--SMAYAGAR 257
            .| |.:..|....:.|:     :.|:.|   ::..||:|.|.      |...|.|  ||....:|
  Rat   209 GVSLQELNPEMGTDNDSENWKEVHKMVV---DSAYEVIKLKGYTNWAIGLSVADLIESMLKNLSR 270

  Fly   258 F--AGSLLKGLNGEKNVIECSYVQSTVTEATFFSTPLVLGKNGVQENLGLPKLNDYEKKLLEAAI 320
            .  ..:::||:.|.:|.:             |.|.|.:|...|:...:        .:||.:..:
  Rat   271 IHPVSTMVKGMYGIENEV-------------FLSLPCILNARGLTSVI--------NQKLKDDEV 314

  Fly   321 PELKK------NIQKGI 331
            .:|:|      :|||.:
  Rat   315 AQLRKSADTLWDIQKDL 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdh2	NP_650696.1	MDH_glyoxysomal_mitochondrial	25..334	CDD:133422	86/341 (25%)
Ldhb	NP_001303262.1	LDH_1	20..330	CDD:133429	86/339 (25%)
		PTS1	339..341