Protein Alignment Mdh2 and ldh-1

DIOPT Version :9

• Sequence 1: NP_650696.1
• Gene: Mdh2 / 42185
• FlyBaseID: FBgn0262559
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_001343759.1
• Gene: ldh-1 / 174798
• WormBaseID: WBGene00002262
• Length: 336
• Species: Caenorhabditis elegans
• Alignment Length: 364
• Identity: 94/364 - (25%)
• Similarity: 155/364 - (42%)
• Gaps: 71/364 - (19%)

  Fly     2 LKQVTKQLALQGVRTFSVGQQNNYKVTVCGAAGGIGQPLSLLLKQNPLVTDLALYDIV--HTPGV 64
            :|:|..::|       :..:.::.||||.| .|.:|...:..:.|..|..:|.|.|:|  ...|.
 Worm     8 IKEVFAEIA-------APVENSHGKVTVVG-VGQVGMACAYSILQQNLANELCLVDVVADKLKGE 64

  Fly    65 AADLSH--IDTKSKTAGFIGADQLGDSLKGSDVVVIPAGVPRKPGMTRDDLFNVNAGIIKDISNS 127
            ..||.|  ..|:..|   :.||.......||.:.|:.||..::.|.||..|...|..|.|.|...
 Worm    65 MMDLQHGLAFTRHCT---VKADTDYSITAGSKLCVVTAGARQREGETRLSLVQRNVEIFKGIIPQ 126

  Fly   128 IAKNCPKALVAIITNPVNTCVPIAAEILKKAGVYDPKRLFGVST-LDVVRARAFIGHALGVDPQT 191
            :.|..|...:.:::|||:    :...:..|......:|:||..| ||..|.|..:...|.:.|.:
 Worm   127 LVKYSPDTCILVVSNPVD----VLTYVTWKLSGLPRERVFGSGTNLDSARFRFLLSEKLNIAPSS 187

  Fly   192 VQIPVIGGH--------SGVTILPV-LSQSQPLF---KGNQDTIEKLTVRIQEAGTEVVKAKAGA 244
            ....:||.|        |||.:..| |.:.:|..   ..|:....::..::.::..|::|.|...
 Worm   188 CHGWIIGEHGDSSVAVWSGVNVAGVTLHEIKPDIGEKTDNEHWEAEIHKKVVDSAYEIIKLKGYT 252

  Fly   245 GSAT-LSMA------YAGAR--FAGSL-LKGLNGEKNVIECSYVQSTVTEATFFSTPLVLGKNG- 298
            ..|. ||:|      ::.:|  ||.|. :||.:|             :.:..:.|.|:|||..|
 Worm   253 SWAIGLSVAKIAQGIFSNSRNVFALSTNVKGFHG-------------INDDVYLSLPVVLGSAGL 304

  Fly   299 ---VQENL---GLPKLNDYEKKLLEAAIPELKKNIQKGI 331
               |::.|   .:.||::..|.|||         :|.||
 Worm   305 THVVKQQLTEAEVQKLHNSAKALLE---------VQNGI 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdh2	NP_650696.1	MDH_glyoxysomal_mitochondrial	25..334	CDD:133422	91/341 (27%)
ldh-1	NP_001343759.1	LDH_1	36..333	CDD:133429	82/325 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810