DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7168 and commd2

DIOPT Version :9

Sequence 1:	NP_650695.1	Gene:	CG7168 / 42184	FlyBaseID:	FBgn0038586	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_001002421.1	Gene:	commd2 / 436694	ZFINID:	ZDB-GENE-040718-118	Length:	199	Species:	Danio rerio

Alignment Length:	232	Identity:	74/232 - (31%)
Similarity:	119/232 - (51%)	Gaps:	39/232 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LRLTQQQRNHLSLLQKPASAVV-ELCKSAFDYLINGPNPSRYEMLAKKSSDLGSPEAVQQAVEAL 67
            |.|:::.:.||..|.:...||| |..:.|.::|..|.||..||..|:|.|  .|.|:||..||.|
Zfish     3 LVLSEEHKEHLGFLSEVDPAVVGEFGRIAVEFLKKGSNPKIYEGAARKLS--VSSESVQHGVEGL 65

  Fly    68 ISLLISVTTRVGSSSVD-MEAILRQTFPELGDDVIEVLEQFVTSKRNFVEGSIKSA-NIRAYRLV 130
            : .|::.::::..|.:| .:::|...|||..:|::  |:.::.:::...:...|.| :|..|.
Zfish    66 M-FLLTESSKLMISELDFQDSVLVLGFPEQLNDLL--LQLYLENRKEIRQILSKLAPSIPQYH-- 125

  Fly   131 NLDWRLEVRTASRSLLDQCQVVVTMKLYLHTEPKNENRELLAVDISGRSEQELKAMQEDERLHRK 195
            ||:|||:|:.|||:|..|.:..|||||:|....|                             |.
Zfish   126 NLEWRLDVQLASRALRHQVKPTVTMKLHLEDGAK-----------------------------RS 161

  Fly   196 DLLVQTDVCSLVHMIKTLEDALAESKTRRIRNIVDGI 232
            ..::|||..:|.|:|:.||.||||.|:...|.|:..|
Zfish   162 AHVLQTDPATLQHLIQELERALAELKSNHCRRILRNI 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7168	NP_650695.1	Commd	26..224	CDD:297546	63/199 (32%)
commd2	NP_001002421.1	Commd2	26..190	CDD:240098	63/199 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588153
Domainoid	1	1.000	45	1.000	Domainoid score	I12233
eggNOG	1	0.900	-	-		E1_28MHC
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I5161
OMA	1	1.010	-	-		QHG55677
OrthoDB	1	1.010	-	-		D1458356at2759
OrthoFinder	1	1.000	-	-		FOG0008101
OrthoInspector	1	1.000	-	-		oto40845
orthoMCL	1	0.900	-	-		OOG6_106223
Panther	1	1.100	-	-	LDO	PTHR15857
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5388
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.800