DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Non3 and rpf2

DIOPT Version :9

Sequence 1:	NP_650694.2	Gene:	Non3 / 42183	FlyBaseID:	FBgn0038585	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_999913.1	Gene:	rpf2 / 406587	ZFINID:	ZDB-GENE-040426-2501	Length:	308	Species:	Danio rerio

Alignment Length:	289	Identity:	138/289 - (47%)
Similarity:	192/289 - (66%)	Gaps:	6/289 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IRKPKTRKGKKVLLAREPQLIESARTMLFLDGRKCGGNVKLCMKDLQALKKPLVKVLNRKNDITP 70
            |.|.|||:.|:.|.:||.:|.|:.:..:.:.|......|...:||:.|||||...:..:||.:.|
Zfish     7 IVKAKTRRSKRFLESRESKLKENPKNSMIIKGGNTSSTVSQALKDVYALKKPNAVLYKKKNMVRP 71

  Fly    71 FDDPSSLEFLTMKNDAALFTFGSTSKKRPDNIILGRIFENEVLDMFELGIKRYQAISEFKNEKIG 135
            |:|.::|||.:.|:|.:||.|||.:||||:|:|.||:|:..|||||||||:.::::::.|.:|..
Zfish    72 FEDSTALEFFSKKSDCSLFLFGSHNKKRPNNLIFGRMFDFHVLDMFELGIENFRSLTDIKMDKCP 136

  Fly   136 ACVKPCLVFNGPKWAQTEELRRLRNLFIDTFQREKVDSIRLQGIEHVLSFTVTDDMNILMRSYRI 200
            ...||.|||.|..:....|.:||:::..|.|...:|.::||.|:||||.||..:. .|.||||::
Zfish   137 EGTKPMLVFAGDLFETDREYQRLKSVLTDFFCGPRVSAVRLAGLEHVLHFTALEG-KIYMRSYKV 200

  Fly   201 LLKKSGQRTPRIELEEIGPSADFSIRRTKIASEDLYKQARKQPKQLKVGKKKNISTDALGNTKGR 265
            ||||||.|||||||||||||.||::||...||:||||.|.:|||..|..||||||.||.|...||
Zfish   201 LLKKSGCRTPRIELEEIGPSFDFTMRRNHTASDDLYKTAHRQPKGAKPKKKKNISHDAFGTRLGR 265

  Fly   266 VHLGKQQTGSIQTRRVKALRK-----TPE 289
            :|:.||....:|||::|.|||     ||:
Zfish   266 LHMQKQDLNKLQTRKMKGLRKRRAEHTPD 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Non3	NP_650694.2	Brix	3..290	CDD:412658	138/289 (48%)
rpf2	NP_999913.1	Brix	8..286	CDD:294606	133/278 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581775
Domainoid	1	1.000	183	1.000	Domainoid score	I3377
eggNOG	1	0.900	-	-		E1_COG5106
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6404
Inparanoid	1	1.050	265	1.000	Inparanoid score	I3046
OMA	1	1.010	-	-		QHG53948
OrthoDB	1	1.010	-	-		D434863at33208
OrthoFinder	1	1.000	-	-		FOG0005406
OrthoInspector	1	1.000	-	-		oto41195
orthoMCL	1	0.900	-	-		OOG6_102220
Panther	1	1.100	-	-	LDO	PTHR12728
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1197
SonicParanoid	1	1.000	-	-		X3835
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800