DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7183 and CG14965

DIOPT Version :9

Sequence 1:	NP_001262701.1	Gene:	CG7183 / 42181	FlyBaseID:	FBgn0038583	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	NP_647783.3	Gene:	CG14965 / 38388	FlyBaseID:	FBgn0035414	Length:	557	Species:	Drosophila melanogaster

Alignment Length:	477	Identity:	92/477 - (19%)
Similarity:	169/477 - (35%)	Gaps:	139/477 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 ELLRKQHEVRVAKATKASAADFRPTKSAGNKEKSSDQGYKKVASSDDGAKVYEAEDHAQLEKSRR 85
            |:|..:.|..|....|.:.|....|.|  ....:..|....:.|              ||:.|..
  Fly   163 EVLATEQEQPVVHTEKTTVAHKSSTTS--TSASAMPQNILDIIS--------------QLQPSLG 211

  Fly    86 ILEAKSKFYDR-MSRNGGSLNSDDNCLVMFNRK--KQEADREPEQCTQRRESRQRLSSSSSSSQD 147
            |     |...| :.|..||    :|.|.....:  |::.|...:..|..:||.:::.|.|
  Fly   212 I-----KLIKRPVKRQSGS----ENELFQLEEQLPKEQTDDTSKMRTVTKESEKQIKSKS----- 262

  Fly   148 EEGHDDLEVEYVDCLGRTRKCLRKDLKEAKRRDKQLAESMPERLD-QTKANWMINTKGSRELNSN 211
                                |:...:|..|..||...:.:|.|.: :.....::..:|.:|.:::
  Fly   263 --------------------CIIDVMKMPKLADKCQEKQVPTRKEYRPIKGTVVRKRGMQEADAD 307

  Fly   212 HNSDDESFIGPRPTESVFSEALSTMTKHDEQRMNWERKEQENFEKPDVH--------------YQ 262
            ..::|||                  ||...::    ||..:..:|.|.|              .|
  Fly   308 RLNEDES------------------TKEQAKK----RKLPQEAQKTDSHASPENGTILNRYTQLQ 350

  Fly   263 DVFFDEARTHGVGYYAFSTDEDERRQQQLDLEKARQATKAKQMRRDELRAQRDRLVADRVLAAKN 327
            :.|:||.:|..:        |...:..|::|..:::.:::..: .:.|......|..:..|:..:
  Fly   351 EKFWDEQKTPML--------EKPTQSIQINLSSSKENSQSDSI-SETLSESFLNLEENIPLSTDS 406

  Fly   328 RIRERNGLPPISEEDYLREE--------QQKKDELAKEEAELNRAEQE--------RRAAIERKK 376
            .........|.|.||..|::        |.:.::|::|.|:|.|.:.|        :..|:...|
  Fly   407 EDESEPDEKPSSSEDAHRDKLLQEYDKLQAEFEKLSEENAKLKRLQAESPWTSAAIKPTALSLSK 471

  Fly   377 EKEEAELEE---------LRKE-----HVRDWDKNKPGVRKLADSESAEPPEEEWKYKAE----R 423
            .:....:::         ||.|     ..|.|   |...|:.| :|..:..:|.:||..:    |
  Fly   472 PQLYMAIKKYVGPTMAALLRMEMFGGSEERTW---KDDEREFA-TELLQLGDEVYKYCCDEWRFR 532

  Fly   424 LPMSQ--EEWNEKQRAQRHAEF 443
            ||..:  ..|.||:..:...||
  Fly   533 LPSMRIARSWLEKKNTENSEEF 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7183	NP_001262701.1	DUF4078	248..328	CDD:290039	16/93 (17%)
CG14965	NP_647783.3	THAP	5..86	CDD:214951
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28PWN
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900