Protein Alignment RAB8A and RabX1

DIOPT Version :10

• Sequence 1: NP_005361.2
• Gene: RAB8A / 4218
• HGNCID: 7007
• Length: 207
• Species: Homo sapiens
• Sequence 2: NP_524713.1
• Gene: RabX1 / 44172
• FlyBaseID: FBgn0015372
• Length: 261
• Species: Drosophila melanogaster
• Alignment Length: 175
• Identity: 63/175 - (36%)
• Similarity: 100/175 - (57%)
• Gaps: 5/175 - (2%)

Human    10 KLLLIGDSGVGKTCVLFRFSEDAFN--STFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRT 72
            |:|::|..|||||.::.|:.::..:  .:.:.||.:.|....|.||..:|||||||||||||:|.
  Fly     7 KVLVLGSRGVGKTRLVIRYIKNTLHRKESEVPTIAVSFFTCNIILDEVKIKLQIWDTAGQERYRA 71

Human    73 ITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGE 137
            :...|||.|...:||:|:|..|:|..|::||:.:..:....:...::|||.|:..:|.||:|...
  Fly    72 VAPMYYRNANAAILVFDLTQYKTFTEIKSWIQELHRNVQDPMILTLVGNKMDMQAQRAVSREEAF 136

Human   138 KLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSP 182
            ..|...|..:.|||.:.:..:|..|.:.|:.:....|   ||.||
  Fly   137 VFATSIGATYFETSTETDQGLEQVFISTAQGLVRLAD---EGKSP 178

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB8A	NP_005361.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	58/163 (36%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		2/15 (13%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		10/16 (63%)
RabX1	NP_524713.1	Rab	7..166	CDD:206640	57/158 (36%)