Protein Alignment RAB8A and Rab1

DIOPT Version :10

• Sequence 1: NP_005361.2
• Gene: RAB8A / 4218
• HGNCID: 7007
• Length: 207
• Species: Homo sapiens
• Sequence 2: NP_732610.1
• Gene: Rab1 / 42524
• FlyBaseID: FBgn0285937
• Length: 205
• Species: Drosophila melanogaster
• Alignment Length: 191
• Identity: 105/191 - (54%)
• Similarity: 141/191 - (73%)
• Gaps: 5/191 - (2%)

Human     5 YDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQER 69
            |||||||||||||||||:|:|.||::|.:..::|||||:||||||||||||.|||||||||||||
  Fly     8 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 72

Human    70 FRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKE 134
            |||||::|||||.||::|||.|:::||:|::.|:..||.:|..:|.|:::|||.|:..|:.|...
  Fly    73 FRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDHT 137

Human   135 RGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSNQGVKITPDQ 195
            ...:.|...||.|:|||||:..|||.||.|:|.:||.::     |.....::...|:..||
  Fly   138 TAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRV-----GPPSSATDNASKVKIDQ 193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB8A	NP_005361.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	100/165 (61%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		6/13 (46%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		14/16 (88%)
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	99/164 (60%)