Protein Alignment RAB8A and Rab11

DIOPT Version :10

• Sequence 1: NP_005361.2
• Gene: RAB8A / 4218
• HGNCID: 7007
• Length: 207
• Species: Homo sapiens
• Sequence 2: NP_477170.1
• Gene: Rab11 / 42501
• FlyBaseID: FBgn0015790
• Length: 214
• Species: Drosophila melanogaster
• Alignment Length: 204
• Identity: 93/204 - (45%)
• Similarity: 133/204 - (65%)
• Gaps: 10/204 - (4%)

Human     5 YDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQER 69
            ||||||::|||||||||:.:|.||:.:.||....||||::|..|:||:|||.||.||||||||||
  Fly     8 YDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKTIKAQIWDTAGQER 72

Human    70 FRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKE 134
            :|.||:||||||:|.:|||||....:::|:..|:|.:.:||..::..|::|||.|:...|.|..:
  Fly    73 YRAITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHADQNIVIMLVGNKSDLRHLRSVPTD 137

Human   135 RGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQG-----SNQ---GVK- 190
            ..:..|...|:.|:||||..:.|||.||..:..:|...:.:|...:.|:|     ||.   .||
  Fly   138 EAKLFAERNGLSFIETSALDSTNVETAFQNILTEIYRIVSQKQIRDPPEGDVIRPSNVEPIDVKP 202

Human   191 -ITPDQQKR 198
             :|.|.:|:
  Fly   203 TVTADVRKQ 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB8A	NP_005361.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	82/165 (50%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		6/13 (46%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		13/16 (81%)
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	81/163 (50%)