Protein Alignment RAB8A and Rab23

DIOPT Version :10

• Sequence 1: NP_005361.2
• Gene: RAB8A / 4218
• HGNCID: 7007
• Length: 207
• Species: Homo sapiens
• Sequence 2: NP_649574.1
• Gene: Rab23 / 40701
• FlyBaseID: FBgn0037364
• Length: 268
• Species: Drosophila melanogaster
• Alignment Length: 187
• Identity: 67/187 - (35%)
• Similarity: 109/187 - (58%)
• Gaps: 4/187 - (2%)

Human    10 KLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTIT 74
            |::::|:.||||:.::.|:.:..|...:..|||:||..|.||:||:.:::.:|||||||.|..||
  Fly    39 KVVIVGNGGVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIEIDGEDVRIMLWDTAGQEEFDCIT 103

Human    75 TAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKL 139
            .||||||...:||:..|:..|||.|::|.|.:|...: ::..:|:.||.|:.::..|:.:..|.|
  Fly   104 KAYYRGAQASVLVFSTTDRASFDAIKDWKRKVENECN-EIPTVIVQNKIDLIEQAVVTADEVETL 167

Human   140 ALDYGIKFMETSAKANINVENAFFTLARDIKAKMDK---KLEGNSPQGSNQGVKITP 193
            |.....:.:.||.|.:|||.:.|..||......|.:   ::.||....|:.....||
  Fly   168 AKLLNCRLIRTSVKEDINVASVFRYLATKCHQLMTQSYDQVAGNQQNSSHPPYSSTP 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB8A	NP_005361.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	61/161 (38%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		4/13 (31%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		12/16 (75%)
Rab23	NP_649574.1	Rab23_like	50..197	CDD:133306	56/147 (38%)