Protein Alignment RAB8A and Rab19

DIOPT Version :9

• Sequence 1: NP_005361.2
• Gene: RAB8A / 4218
• HGNCID: 7007
• Length: 207
• Species: Homo sapiens
• Sequence 2: NP_001261575.1
• Gene: Rab19 / 38930
• FlyBaseID: FBgn0015793
• Length: 219
• Species: Drosophila melanogaster
• Alignment Length: 195
• Identity: 87/195 - (44%)
• Similarity: 130/195 - (66%)
• Gaps: 7/195 - (3%)

Human     5 YDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQER 69
            :|:|||::||||.|.||||::.||....:.....:|||:||.::||.::||:|||||||||||||
  Fly    18 FDFLFKIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAVEGKQIKLQIWDTAGQER 82

Human    70 FRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKE 134
            |||||.:|||.|.|:::|||||...||.|::.||..:..:.:::|..:::|||||:.::|:|..|
  Fly    83 FRTITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYTASNVLIILVGNKCDLEEQREVDFE 147

Human   135 RGEKLA--LDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSNQGVKITPDQQK 197
            ...::.  :...:..||||||.|:|||:||..||.::|.:.|.......|:.:     ||..|.|
  Fly   148 EARQMCQYIPEILFVMETSAKENMNVEDAFRCLANELKRQHDANNVEEVPENT-----ITLGQGK 207

Human   198  197
              Fly   208  207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB8A	NP_005361.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	81/167 (49%)
		Effector region. /evidence=ECO:0000250	37..45		3/7 (43%)
Rab19	NP_001261575.1	Rab19	19..184	CDD:133267	80/164 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910