Protein Alignment RAB8A and Rab32

DIOPT Version :10

• Sequence 1: NP_005361.2
• Gene: RAB8A / 4218
• HGNCID: 7007
• Length: 207
• Species: Homo sapiens
• Sequence 2: NP_525109.1
• Gene: Rab32 / 35940
• FlyBaseID: FBgn0002567
• Length: 686
• Species: Drosophila melanogaster
• Alignment Length: 194
• Identity: 63/194 - (32%)
• Similarity: 108/194 - (55%)
• Gaps: 11/194 - (5%)

Human     1 MAKTYD---YLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRI-KLQI 61
            |..|.|   :|:|:|:||:.|.|||..:.|:....|:..:.:|||:||.::.::.|...| :||:
  Fly   473 MTSTSDKREHLYKILVIGELGTGKTSFIKRYVHQFFSQNYRATIGVDFALKVLQWDANTIVRLQL 537

Human    62 WDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHA----SADVEKMILGNK 122
            ||.||||||..:|..||:.|:|..:|:|:|...:||.:..|..:::...    .:.:..::|.||
  Fly   538 WDIAGQERFGNMTRVYYKEAVGAFIVFDVTRSGTFDCVSKWKEDLDSKVQLPDGSPIPCILLANK 602

Human   123 CDVNDKRQVSK-ERGEKLALDYGIK-FMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQG 184
            ||...:..::: |:.::...:.|.. :.|||||.|||::.|...|...|... ||.:..:...|
  Fly   603 CDQEKQGIITQPEKMDEYVRENGFAGWFETSAKENINIDEAARALVNKILIN-DKLISADLADG 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB8A	NP_005361.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	58/175 (33%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		4/13 (31%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		10/16 (63%)
Rab32	NP_525109.1	PHA03247	<126..481	CDD:223021	3/7 (43%)
		Rab32_Rab38	484..686	CDD:206692	59/183 (32%)