Protein Alignment RAB8A and Rab2

DIOPT Version :10

• Sequence 1: NP_005361.2
• Gene: RAB8A / 4218
• HGNCID: 7007
• Length: 207
• Species: Homo sapiens
• Sequence 2: NP_477090.1
• Gene: Rab2 / 35577
• FlyBaseID: FBgn0014009
• Length: 213
• Species: Drosophila melanogaster
• Alignment Length: 193
• Identity: 89/193 - (46%)
• Similarity: 132/193 - (68%)
• Gaps: 12/193 - (6%)

Human     4 TYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQE 68
            :|.||||.::|||:||||:|:|.:|::..|......|||::|..|.|.:|||:||||||||||||
  Fly     2 SYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQE 66

Human    69 RFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSK 133
            .||:||.:|||||.|.:||||||..::|:::..|:.:..:|:::::..|::|||.|::.:|:|.|
  Fly    67 AFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVKK 131

Human   134 ERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKM-----DKKLEGNSPQGSNQGVKI 191
            |.||..|.::|:.||||||:...|||.||...|::|..|:     |...|.|       |:||
  Fly   132 EEGEAFAREHGLVFMETSARTAANVEEAFINTAKEIYEKIQEGVFDINNEAN-------GIKI 187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB8A	NP_005361.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	81/165 (49%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		4/13 (31%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		12/16 (75%)
Rab2	NP_477090.1	PLN03108	1..213	CDD:178655	89/193 (46%)