Protein Alignment RAB8A and Rab6

DIOPT Version :10

• Sequence 1: NP_005361.2
• Gene: RAB8A / 4218
• HGNCID: 7007
• Length: 207
• Species: Homo sapiens
• Sequence 2: NP_477172.1
• Gene: Rab6 / 34636
• FlyBaseID: FBgn0015797
• Length: 208
• Species: Drosophila melanogaster
• Alignment Length: 191
• Identity: 82/191 - (42%)
• Similarity: 122/191 - (63%)
• Gaps: 5/191 - (2%)

Human     9 FKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTI 73
            |||:.:|:..||||.::.||..|:|::|:.:||||||..:|:.|:.:.::||:||||||||||::
  Fly    13 FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSL 77

Human    74 TTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEK 138
            ..:|.|.:...::||||||..||.....||.::.....:||..|::|||.|::||||||.|.||:
  Fly    78 IPSYIRDSTVAVVVYDITNTNSFHQTSKWIDDVRTERGSDVIIMLVGNKTDLSDKRQVSTEEGER 142

Human   139 LALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSNQGV--KITPDQQK 197
            .|.:..:.|:||||||..||:..|..:|..:.. ||.  ..|.|....|.|  |.:|::.|
  Fly   143 KAKELNVMFIETSAKAGYNVKQLFRRVAAALPG-MDS--TENKPSEDMQEVVLKDSPNETK 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB8A	NP_005361.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	73/162 (45%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		7/13 (54%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		10/16 (63%)
Rab6	NP_477172.1	Rab6	13..173	CDD:206654	73/159 (46%)