Protein Alignment RAB8A and Rab21

DIOPT Version :10

• Sequence 1: NP_005361.2
• Gene: RAB8A / 4218
• HGNCID: 7007
• Length: 207
• Species: Homo sapiens
• Sequence 2: NP_001036321.2
• Gene: Rab21 / 3355163
• FlyBaseID: FBgn0039966
• Length: 222
• Species: Drosophila melanogaster
• Alignment Length: 175
• Identity: 67/175 - (38%)
• Similarity: 108/175 - (61%)
• Gaps: 1/175 - (0%)

Human     9 FKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIEL-DGKRIKLQIWDTAGQERFRT 72
            ||.:|:|:..||||.::.|:.||.||:..:||:...|..|.:.| ||:|.:|.||||||||||..
  Fly    14 FKAVLLGEGCVGKTSLVLRYMEDRFNAQHLSTLQASFVSRKMSLEDGRRAQLNIWDTAGQERFHA 78

Human    73 ITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGE 137
            :...||||:.|.:||||||:..||..:::|:|.:.:....::..:|:|||.|:.::|.|:.:...
  Fly    79 LGPIYYRGSDGALLVYDITDRDSFQKVKSWVRELRQMRGTEIALIIVGNKTDLEEQRAVTHDEAL 143

Human   138 KLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSP 182
            :.|...|.:::|||||.|..|...|..|.:.:..::.::....||
  Fly   144 QYARTVGAQYVETSAKENEGVAELFELLTQLMLEQLSQRQPDASP 188

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB8A	NP_005361.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	65/163 (40%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		5/13 (38%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		10/16 (63%)
Rab21	NP_001036321.2	Rab21	14..176	CDD:133323	65/161 (40%)