Protein Alignment RAB8A and Rab10

DIOPT Version :10

• Sequence 1: NP_005361.2
• Gene: RAB8A / 4218
• HGNCID: 7007
• Length: 207
• Species: Homo sapiens
• Sequence 2: NP_523419.1
• Gene: Rab10 / 33025
• FlyBaseID: FBgn0015789
• Length: 204
• Species: Drosophila melanogaster
• Alignment Length: 202
• Identity: 139/202 - (68%)
• Similarity: 166/202 - (82%)
• Gaps: 3/202 - (1%)

Human     3 KTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQ 67
            ||||.||||||||||||||||:|||||:|||.|||||||||||||:|:||.||:|||||||||||
  Fly     4 KTYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQ 68

Human    68 ERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVS 132
            |||.||||:||||||||||||||||||||:||..|:|||:|||:.||||||||||||:.|||.|:
  Fly    69 ERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVN 133

Human   133 KERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSNQGVKITPDQQK 197
            |||||.:|.::||:|||||||:|||:|.||..||   :|.:||.....|.:...:.:....:|:|
  Fly   134 KERGEAIAREHGIRFMETSAKSNINIERAFCELA---EAILDKTSGRESAENQERVIIDRRNQEK 195

Human   198 RSSFFRC 204
            ...:.:|
  Fly   196 APGYSKC 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB8A	NP_005361.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	129/165 (78%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		12/13 (92%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		14/16 (88%)
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	130/168 (77%)