Protein Alignment RAB8A and RabX2

DIOPT Version :10

• Sequence 1: NP_005361.2
• Gene: RAB8A / 4218
• HGNCID: 7007
• Length: 207
• Species: Homo sapiens
• Sequence 2: NP_572627.1
• Gene: RabX2 / 31971
• FlyBaseID: FBgn0030200
• Length: 195
• Species: Drosophila melanogaster
• Alignment Length: 165
• Identity: 78/165 - (47%)
• Similarity: 112/165 - (67%)
• Gaps: 0/165 - (0%)

Human     5 YDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQER 69
            :|||||:|::|||||||:|:|.|||:|.|...::.|:|||.|.|::||..:.:.||:|||:|.:|
  Fly     4 FDYLFKVLVLGDSGVGKSCLLMRFSDDRFTEKYLRTMGIDVKARSVELVSRVMMLQVWDTSGDKR 68

Human    70 FRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKE 134
            |.::..:.||.|.||:||||||:.|||.||..|::.|.......|..:::|||.|..:.||||.|
  Fly    69 FNSLMPSNYRSAHGILLVYDITSSKSFQNIDGWMKEIRRMCPDKVTVLLVGNKSDDPNHRQVSME 133

Human   135 RGEKLALDYGIKFMETSAKANINVENAFFTLARDI 169
            :|...|....:.|.|.|||:.:||.:.|.:||.||
  Fly   134 QGFNYAHRGALGFEEVSAKSGMNVYDIFSSLAMDI 168

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB8A	NP_005361.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	78/164 (48%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		5/13 (38%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		6/16 (38%)
RabX2	NP_572627.1	Rab	8..165	CDD:206640	71/156 (46%)