Protein Alignment RAB8A and Rab39

DIOPT Version :10

• Sequence 1: NP_005361.2
• Gene: RAB8A / 4218
• HGNCID: 7007
• Length: 207
• Species: Homo sapiens
• Sequence 2: NP_572405.2
• Gene: Rab39 / 31684
• FlyBaseID: FBgn0029959
• Length: 218
• Species: Drosophila melanogaster
• Alignment Length: 177
• Identity: 77/177 - (43%)
• Similarity: 118/177 - (66%)
• Gaps: 11/177 - (6%)

Human     5 YDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIEL-DGKRIKLQIWDTAGQE 68
            ::|.|:|:|||||.|||:.:|..|::..|......|:|:||..|.||: ||.:||||:|||||||
  Fly     6 FEYQFRLILIGDSTVGKSSLLKFFTDGKFAELSDPTVGVDFFARLIEMKDGTQIKLQLWDTAGQE 70

Human    69 RFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWI----RNIEEHASADVEKMILGNKCDV---N 126
            |||:||.:|||.::|::|||||:|..||::|..|:    |:||.|.....   ::|.|.|:   .
  Fly    71 RFRSITKSYYRNSVGVLLVYDISNHASFEHIPLWMMEAQRHIEPHRPVFA---LVGCKLDLINAG 132

Human   127 DKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKM 173
            ..|:|:.|..:|.|..:|:.|:||||::..|||.||..:.:::.|::
  Fly   133 GHREVTTEEAQKFAKQHGLHFVETSARSGANVEEAFRMVTQEVYARI 179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB8A	NP_005361.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	76/173 (44%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		3/13 (23%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		13/16 (81%)
Rab39	NP_572405.2	Rab39	8..218	CDD:133311	77/175 (44%)