Protein Alignment CG7985 and hex-3

DIOPT Version :9

• Sequence 1: NP_001262699.1
• Gene: CG7985 / 42178
• FlyBaseID: FBgn0028499
• Length: 708
• Species: Drosophila melanogaster
• Sequence 2: NP_499390.3
• Gene: hex-3 / 189716
• WormBaseID: WBGene00012663
• Length: 591
• Species: Caenorhabditis elegans
• Alignment Length: 596
• Identity: 171/596 - (28%)
• Similarity: 277/596 - (46%)
• Gaps: 89/596 - (14%)

  Fly   108 PTQAKKAPLPMSESFLFEQERLKILEQQQRQRNA--GMEELNANAEDERMLSSAERQTQYEHELQ 170
            |.||.||..|.:      .|..|...:|.....|  ..|.:..|.|....||
 Worm    57 PLQAPKAQEPAA------AETTKKPSRQPHHTTAKPRTENVEINGEKYPKLS------------- 102

  Fly   171 RMGVPVVAGIGPDGPRAPAERLVHLDLKGAPPKLSFLKQLLPVLRALGATGLLIEYEDMFPYSGV 235
                       |||...|..|:|||||||||.|..|..:|......:.|||:|:|:|||||:.|.
 Worm   103 -----------PDGNLIPQRRIVHLDLKGAPYKPEFFTELFAFFNRIQATGILLEWEDMFPFKGR 156

  Fly   236 LQPLAAHNAYKEDELRDFLECAALHGLSVMPLVQTFGHMEYVLKLSGFEQLRELAESPQSICPSQ 300
            |:.....|||..:.:...|:.|..|.|.::|||||.||:|::|||..|..|||....||.||.|.
 Worm   157 LRGAINKNAYSMETVEHILQEAQKHHLQIIPLVQTMGHLEWILKLEEFAHLREDTRFPQVICFSD 221

  Fly   301 PQSMALLEQMLTQVIELHSQCLGQATPATNVPVARIRFTHIHIGCDEVQRMGECTTCRQRLRSE- 364
            ..:..|:::|:.:|..:|.               :...::.|||.||..::|.|.....:::.|
 Worm   222 ENAWELIKEMIEEVANVHK---------------KYGMSYFHIGADEAFQIGICNASITQIKKEF 271

  Fly   365 ----LFLSHVVSMAHFIRRQWPHLGVVIWDDQLRSMSLSELQHSQVGSYVEPMVWVYASDIYRFI 425
                |.|.|:...|.|::.::|...|:.|.|.|.|...|:::..::...::|::|.||.|:..::
 Worm   272 TRERLMLWHIARTARFVKEKYPETQVLAWHDMLASAMESDIEDYKLTELLQPVLWNYAEDLDIYL 336

  Fly   426 QPQLWDTYAKVFPSAWTASAFKGAFGESLLVPPLQHHLENNIRWL---AVIAKEGGRFSKGLRGL 487
            ....| ...:.|.:.|.:||:|||.|.:.......|:|:|:..|:   .::.|:    .:.:.||
 Worm   337 PRSTW-MILRNFRNVWGSSAWKGADGPARYSTNANHYLKNHESWIKQFTMVYKD----FEVVEGL 396

  Fly   488 ALTGWQRYDHFAVLCELLPVGIPSLMTSLSTVSKG--YFSTNPRDNELLRVLQCVFQPDSRRSGR 550
            .:.||.||||||||.|.:||.:|:|..|:.|:.:|  .....|..:||   |||.
 Worm   397 IMAGWSRYDHFAVLAETIPVALPTLAMSMETMIEGRPLAGNYPVTSEL---LQCT---------- 448

  Fly   551 PWLELHPNAHHSQLFAVCNYPGHLVFKYALRLFDKLAEIRLYLQQTRDQSAWLS----DYNVRHN 611
            |.|:|...|      ..|.:||:.:::....::.|..::|.|.....:.:.|||    ||:|
 Worm   449 PPLDLGFTA------TGCKFPGNRIYELINEMYQKQMQLRTYRLDDYELNGWLSRVADDYSV--- 504

  Fly   612 FSSPLRVRELTARTPMLIEELRAMAREAQQLLWEVYDEYTVTEFVEQHIYPTIEALQRQLARAEM 676
             ||...:.::.....|....|..:|.:.:..:..::.:.||.||:..::...:|...|:......
 Worm   505 -SSHWYIDKIENMIEMHATPLEQLADDLRFEMERIFFKDTVDEFIFTYLGEDLEWFNRKRETIRK 568

  Fly   677 LLQRRTWPQRP 687
            :...:|:|:||
 Worm   569 VSTSQTFPKRP 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7985	NP_001262699.1	DUF737	78..>170	CDD:283062	15/63 (24%)
		GH20_GcnA-like	191..517	CDD:119335	113/333 (34%)
hex-3	NP_499390.3	GH20_GcnA-like	112..425	CDD:119335	112/332 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159019
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_arCOG07452
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68120
Inparanoid	1	1.050	249	1.000	Inparanoid score	I2011
Isobase	1	0.950	-	0	Normalized mean entropy	S7178
OMA	1	1.010	-	-		QHG46370
OrthoDB	1	1.010	-	-		D1021041at2759
OrthoFinder	1	1.000	-	-		FOG0003694
OrthoInspector	1	1.000	-	-		otm14575
orthoMCL	1	0.900	-	-		OOG6_105415
Panther	1	1.100	-	-	O	PTHR21040
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7251
SonicParanoid	1	1.000	-	-		X2558
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.750