Protein Alignment CG7985 and hex-2

DIOPT Version :10

• Sequence 1: NP_650689.1
• Gene: CG7985 / 42178
• FlyBaseID: FBgn0028499
• Length: 708
• Species: Drosophila melanogaster
• Sequence 2: NP_504489.3
• Gene: hex-2 / 178951
• WormBaseID: WBGene00015767
• Length: 596
• Species: Caenorhabditis elegans
• Alignment Length: 613
• Identity: 163/613 - (26%)
• Similarity: 290/613 - (47%)
• Gaps: 87/613 - (14%)

  Fly   104 RSLRPTQAK-KAPLPMSESFLFEQERLKILEQQQRQRNAGMEELNANAEDERMLS---SAERQTQ 164
            |:|...|.: :.|:.:.:...||:.....:||:.::.|..:.: .|:.|:.:.::   ..||.::
 Worm    43 RALDSMQKEPQTPVLVQKRENFEESIDVAVEQESKKENPFVNQ-QASTENAKPITQEVKIERPSR 106

  Fly   165 YEHELQRMGVPVVAGIGPDGPRAPAERLVHLDLKGAPPKLSFLKQLLPVLRALGATGLLIEYEDM 229
             ::|..:..|                  :|.||||||||:.:...||.::...||||:|:|:|||
 Worm   107 -DNEFYKNVV------------------IHFDLKGAPPKVDYFLDLLRLIAKGGATGILLEWEDM 152

  Fly   230 FPYSGVLQPLAAHNAYKEDELRDFLECAALHGLSVMPLVQTFGHMEYVLKLSGFEQLRELAES-- 292
            ||::|.|:.....:||.|.::...|..|....|.|:||||||||:|::||   :|::|:..|:
 Worm   153 FPWTGKLEQFKNTDAYSESDVDMILSEATKLKLDVIPLVQTFGHLEWILK---YEEMRKYRENDA 214

  Fly   293 -PQSICPSQPQSMALLEQMLTQVIELHSQCLGQATPATNVPVARIRFTHIHIGCDEVQRMGECTT 356
             ||.:|....:.:..:.:|:.||.:.|               |:......|||.||....|.|..
 Worm   215 YPQVLCLGNEEGVEFVREMIRQVAKKH---------------AKYGIPFFHIGADEAFEFGVCQE 264

  Fly   357 CRQRLRSE--------LFLSHVVSMAHFIRRQ-WPHLGVVIWDDQLRSMSLSELQHSQVGSYVEP 412
            ....::..        |.|:|:.::|.|.::| .....::.|.|.|:......:::.::|..::|
 Worm   265 SLDWIKKNGKNGRKQLLALAHLKAIAEFAKQQTGDSTQILAWHDMLKDFDSRLIKNLELGQIIQP 329

  Fly   413 MVWVYASDIYRFIQPQLWDTYAKVFPSAWTASAFKGAFGESLLVPPLQHHLENNIRWLAVIAKEG 477
            :||.|:.:|.. :...::...|:.||:.|.:||:|||...|.....::|:..||..|:.....:.
 Worm   330 VVWDYSENIIT-LNDYIFSALAENFPTMWASSAYKGANYPSASTSEVRHYETNNRNWIRTKQNQE 393

  Fly   478 GRFSKGLRGLALTGWQRYDHFAVLCELLPVGIPSLMTSLSTVSKGYFSTNPRDNELLR-----VL 537
            .:|..|.:|:.:||||||||.|.|||.||:|..|:|..:...    .:....|.|..|     :|
 Worm   394 RKFKNGFQGIIVTGWQRYDHLAGLCETLPIGTASMMLQMQIA----LNAPALDLEGTRQKAATLL 454

  Fly   538 QCV-FQPDSRRSGRPWLELHPNAHHSQLFAVCNYPG---HLVFKYAL-RLFDKLAEIRLYLQQTR 597
            :|. |..|.       :::..|.        |.|.|   :|:::..: .||   |.|...|.:..
 Worm   455 ECQGFNVDG-------VKVVSNQ--------CKYRGFQTYLIYQSEVPNLF---ARIDSELSKNH 501

  Fly   598 DQSAWLSDYNVRHNFSSPLRVRELTARTPMLIEELRAMAREAQQLLWEVYDEYTVTEFVEQHIYP 662
            ....|.:.||.::|.|.....||:......|:.:...:..:.:..:.::|.|.|:.||:.:::..
 Worm   502 HLMGWANRYNRKYNISQNWYHREMLPFVQQLVGQYDRVESDLRASMKDLYFENTIDEFIYENLGE 566

  Fly   663 TIEALQRQLARAEMLLQRRTWPQRPLPL 690
            ..|.|...|...:.|.:.|.||:|..|:
 Worm   567 MSEKLHGYLEEIQRLDKLRAWPKRHFPI 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7985	NP_650689.1	GH20_GcnA-like	191..517	CDD:119335	109/337 (32%)
hex-2	NP_504489.3	GH20_GcnA-like	113..433	CDD:119335	110/356 (31%)