DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ssdp and Ssbp3

DIOPT Version :9

Sequence 1:	NP_001262698.1	Gene:	Ssdp / 42177	FlyBaseID:	FBgn0011481	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	XP_006503474.1	Gene:	Ssbp3 / 72475	MGIID:	1919725	Length:	410	Species:	Mus musculus

Alignment Length:	478	Identity:	237/478 - (49%)
Similarity:	268/478 - (56%)	Gaps:	124/478 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MYGKSKTSAVPSDAQAREKLALYVYEYLLHVGAQKAAQTFLSEIRWEKNITLGEPPGFLHTWWCV 65
            |:.|.|.||||||.|||||||||||||||||||||:||||||||||||||||||||||||:||||
Mouse     1 MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCV 65

  Fly    66 FWDLYCAAPERRDQCDHSSEAKAFHDYGFVSSGYGVNGIGPGGPHNAGGPAPSP-LGQMPPGGDG 129
            |||||||||||||.|:|||||||||||                   :...|||| ||.:|| .||
Mouse    66 FWDLYCAAPERRDTCEHSSEAKAFHDY-------------------SAAAAPSPVLGNIPP-NDG 110

  Fly   130 GPMGPGGPMGPNFF---PNSTMRPSPPTHASSPQPPPSQMM-PGQPPFMGGPRYPGGPRPGVRMQ 190
               .||||:.|.||   |.|  :|||  ||..|...||.|| |...||| .|||.|||||.:|
Mouse   111 ---MPGGPIPPGFFQGPPGS--QPSP--HAQPPPHNPSSMMGPHSQPFM-SPRYAGGPRPPIR-- 165

  Fly   191 GMGNEFNGPPG-----QPMMPNSMDPTRPGG--GMGPMNPRMNPPRGPGGMGP----------MG 238
             |||:   |||     ||::||||||||..|  .||....|||||||.|.|||          ..
Mouse   166 -MGNQ---PPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQTDPWLSLQN 226

  Fly   239 YGGPGGMRGP--APGPGGMPPMGMGGAGGRPPQW-QPNAS---------APLNA----YSSSSPG 287
            ||  .|||.|  :.|| .||.:.||...|||  | .||::         ||.::    |||||||
Mouse   227 YG--SGMRPPPNSLGP-AMPGINMGPGAGRP--WPNPNSANSGRQLQSMAPESSFQIPYSSSSPG 286

  Fly   288 NY--GPGSNGPPGPGTPIMPSPQDNTQGGPVGGPGDSMYALMKP--------EFPMGGGPDGGGG 342
            .|  .||..||  |||||||||.|:|..      .|::|.::.|        .||||.|.|
Mouse   287 TYVGPPGGGGP--PGTPIMPSPADSTNS------SDNIYTMINPVPPGGSRSNFPMGPGSD---- 339

  Fly   343 GGGPGGMGPMGG-GPNSMGPVLNGGGGPDGSG-LDGM-KNSPAN-----GGPGTPREDSGSGMGD 399
                |.||.||| .|:.|       .|..||| :||: ||||.|     ..|||||:|...|
Mouse   340 ----GPMGGMGGMEPHHM-------NGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG--- 390

  Fly   400 YNLGGFGGPGENDQTESAAILKI 422
               |.|....:||....:..:.:
Mouse   391 ---GNFLHSFQNDNYSPSMTMSV 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ssdp	NP_001262698.1	SSDP	81..393	CDD:282372	159/367 (43%)
Ssbp3	XP_006503474.1	LisH	17..43	CDD:128913	24/25 (96%)
Ssbp3	XP_006503474.1	SSDP	81..387	CDD:398282	159/367 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	194	1.000	Domainoid score	I3164
eggNOG	1	0.900	-	-		E1_KOG4594
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23411
Inparanoid	1	1.050	351	1.000	Inparanoid score	I2255
Isobase	1	0.950	-	0	Normalized mean entropy	S4617
OMA	1	1.010	-	-		QHG45948
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001190
OrthoInspector	1	1.000	-	-		otm42344
orthoMCL	1	0.900	-	-		OOG6_107792
Panther	1	1.100	-	-	O	PTHR12610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X810
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.780