DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ssdp and SSBP3

DIOPT Version :9

Sequence 1:	NP_001262698.1	Gene:	Ssdp / 42177	FlyBaseID:	FBgn0011481	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_663768.1	Gene:	SSBP3 / 23648	HGNCID:	15674	Length:	388	Species:	Homo sapiens

Alignment Length:	456	Identity:	235/456 - (51%)
Similarity:	262/456 - (57%)	Gaps:	102/456 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MYGKSKTSAVPSDAQAREKLALYVYEYLLHVGAQKAAQTFLSEIRWEKNITLGEPPGFLHTWWCV 65
            |:.|.|.||||||.|||||||||||||||||||||:||||||||||||||||||||||||:||||
Human     1 MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCV 65

  Fly    66 FWDLYCAAPERRDQCDHSSEAKAFHDYGFVSSGYGVNGIGPGGPHNAGGPAPSP-LGQMPPGGDG 129
            |||||||||||||.|:|||||||||||                   :...|||| ||.:|| .||
Human    66 FWDLYCAAPERRDTCEHSSEAKAFHDY-------------------SAAAAPSPVLGNIPP-NDG 110

  Fly   130 GPMGPGGPMGPNFF---PNSTMRPSPPTHASSPQPPPSQMM-PGQPPFMGGPRYPGGPRPGVRMQ 190
               .||||:.|.||   |.|  :|||  ||..|...||.|| |...||| .|||.|||||.:|
Human   111 ---MPGGPIPPGFFQGPPGS--QPSP--HAQPPPHNPSSMMGPHSQPFM-SPRYAGGPRPPIR-- 165

  Fly   191 GMGNEFNGPPG-----QPMMPNSMDPTRPGG--GMGPMNPRMNPPR--GPGGMGPMGYGGPGGMR 246
             |||:   |||     ||::||||||||..|  .||....||||||  ||.|.||..||  .|||
Human   166 -MGNQ---PPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYG--SGMR 224

  Fly   247 GP--APGPGGMPPMGMGGAGGRPPQWQPNASAPLNAYSSSSPGNY--GPGSNGPPGPGTPIMPSP 307
            .|  :.|| .||.:.||...|||  |....||....|||||||.|  .||..||  |||||||||
Human   225 PPPNSLGP-AMPGINMGPGAGRP--WPNPNSANSIPYSSSSPGTYVGPPGGGGP--PGTPIMPSP 284

  Fly   308 QDNTQGGPVGGPGDSMYALMKP--------EFPMGGGPDGGGGGGGPGGMGPMGG-GPNSMGPVL 363
            .|:|..      .|::|.::.|        .||||.|.|        |.||.||| .|:.|
Human   285 ADSTNS------SDNIYTMINPVPPGGSRSNFPMGPGSD--------GPMGGMGGMEPHHM---- 331

  Fly   364 NGGGGPDGSG-LDGM-KNSPAN-----GGPGTPREDSGSGMGDYNLGGFGGPGENDQTESAAILK 421
               .|..||| :||: ||||.|     ..|||||:|...|      |.|....:||....:..:.
Human   332 ---NGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG------GNFLHSFQNDNYSPSMTMS 387

  Fly   422 I 422
            :
Human   388 V 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ssdp	NP_001262698.1	SSDP	81..393	CDD:282372	157/345 (46%)
SSBP3	NP_663768.1	LisH	17..43	CDD:128913	24/25 (96%)
		SSDP	81..365	CDD:398282	157/345 (46%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	101..388		148/335 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	194	1.000	Domainoid score	I3173
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23411
Inparanoid	1	1.050	351	1.000	Inparanoid score	I2275
Isobase	1	0.950	-	0	Normalized mean entropy	S4617
OMA	1	1.010	-	-		QHG45948
OrthoDB	1	1.010	-	-		D387814at33208
OrthoFinder	1	1.000	-	-		FOG0001190
OrthoInspector	1	1.000	-	-		otm40276
orthoMCL	1	0.900	-	-		OOG6_107792
Panther	1	1.100	-	-	O	PTHR12610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X810
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	13	12.930