DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ssdp and ssbp4

DIOPT Version :9

Sequence 1:	NP_001262698.1	Gene:	Ssdp / 42177	FlyBaseID:	FBgn0011481	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	XP_012809287.1	Gene:	ssbp4 / 100488961	XenbaseID:	XB-GENE-994793	Length:	408	Species:	Xenopus tropicalis

Alignment Length:	474	Identity:	246/474 - (51%)
Similarity:	276/474 - (58%)	Gaps:	114/474 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MYGKSKTSAVPSDAQAREKLALYVYEYLLHVGAQKAAQTFLSEIRWEKNITLGEPPGFLHTWWCV 65
            ||.|.|.|.||||:|||||||||||||||||||||:||||||||||||||||||||||||:||||
Frog     1 MYAKGKGSTVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCV 65

  Fly    66 FWDLYCAAPERRDQCDHSSEAKAFHDYGFVSSGYGVNGIGPGGPHNAGGPAPSP-LGQMPPGGDG 129
            |||||||||:||:.|:|||||||||||                   :...|||| :|.||| .||
Frog    66 FWDLYCAAPDRRETCEHSSEAKAFHDY-------------------SAAAAPSPVMGNMPP-NDG 110

  Fly   130 GPMGPGGPMGPNFF---PNSTMRPSPPTHASSPQPPP-----SQMMPGQPPFMGGPRYPGGPRPG 186
               .|||||.|.||   |.|  :|||  ||   ||||     ..|.|...||| .|||||||||.
Frog   111 ---MPGGPMPPGFFQGPPGS--QPSP--HA---QPPPHNPNNPMMGPHSQPFM-SPRYPGGPRPS 164

  Fly   187 VRMQGMGNEFNGPP-----GQPMMPNSMDPTRPGG--GMGPMNPRMNPPRGPGGMGPMGYGGPGG 244
            :||.      |.||     .||::|||||||||.|  .||....|||||||.|.|||..||  .|
Frog   165 LRMP------NQPPVGVPGSQPLLPNSMDPTRPQGHPNMGGPMQRMNPPRGMGAMGPQNYG--SG 221

  Fly   245 MRGP--APGPGGMPPMGMGGAGGRPPQWQPNASAPLNAYSSSSPGNY--GPGSNGPPGPGTPIMP 305
            ||.|  :.|..|||.|.| |.|||.| | ||.:|...||||||||||  .||..||  |||||||
Frog   222 MRPPPNSLGGPGMPGMNM-GPGGRGP-W-PNPNANSIAYSSSSPGNYVGPPGGGGP--PGTPIMP 281

  Fly   306 SPQDNTQG--------GPVGGPGDSMYALMKPEFPMGGGPDGGGGGGGP-GGMGPMGGGPNSMGP 361
            ||.|:|..        .|: |||.|     :|.||||.|||      || ||||.|  .|:.|
Frog   282 SPGDSTNSSENMYTMMNPI-GPGGS-----RPNFPMGPGPD------GPMGGMGAM--EPHHM-- 330

  Fly   362 VLNGGGGPDGSG-LDGM-KNSP-----ANGGPGTPREDSGSGMGDYNLGGFGGPGENDQ-TESAA 418
                 .|..||| :|.: ||||     .|..|||||:|....      |.|..|.:::. ..|:.
Frog   331 -----NGSLGSGDMDVLPKNSPNNMAGMNNPPGTPRDDGEMA------GNFLNPFQSESCPRSSK 384

  Fly   419 ILKIKESMHEEAK--RFEK 435
            :|:    .|::..  ||.:
Frog   385 LLQ----RHDQCNQMRFHR 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ssdp	NP_001262698.1	SSDP	81..393	CDD:282372	167/347 (48%)
ssbp4	XP_012809287.1	LisH	17..43	CDD:128913	24/25 (96%)
ssbp4	XP_012809287.1	SSDP	81..364	CDD:367969	167/347 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	207	1.000	Domainoid score	I2815
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	361	1.000	Inparanoid score	I2150
OMA	1	1.010	-	-		QHG45948
OrthoDB	1	1.010	-	-		D387814at33208
OrthoFinder	1	1.000	-	-		FOG0001190
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X810
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.080