Protein Alignment MED17 and med17

DIOPT Version :9

• Sequence 1: NP_650686.1
• Gene: MED17 / 42175
• FlyBaseID: FBgn0038578
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_001071042.1
• Gene: med17 / 567560
• ZFINID: ZDB-GENE-040302-1
• Length: 643
• Species: Danio rerio
• Alignment Length: 662
• Identity: 279/662 - (42%)
• Similarity: 410/662 - (61%)
• Gaps: 54/662 - (8%)

  Fly     4 SVNISVETTCENQIREIGYDGTELYQPPPTLSESLAKCAARIDFSKTSLDDLKKEEKSAAA---- 64
            :|.:|:|::||.|::|:..||.|.|.||.::|::|||...||||.::|..:....|::.|.
Zfish     6 AVRVSIESSCERQVQEVSLDGMETYVPPLSMSQNLAKLVQRIDFCQSSDSEEDGAERARAGREQW 70

  Fly    65 --AADEDKDATQFQESLWPWDAVRNKLKDALTEICVLSDVISIAKDKRYLVLDPLLEE--ADDTK 125
              ..:||:...:||.||||||:|||.|:.||||:|||.||:|:.|:::|:.|||:.::  ...|.
Zfish    71 KQEPEEDEGQLKFQPSLWPWDSVRNNLRSALTEMCVLHDVLSVLKERKYMTLDPVSQDPAMAKTP 135

  Fly   126 PIVQVYSRKKAISQAAQVLLSGAERLRNAHSE-QRNRNVSDFHIELLRLRQNWRLKKVSNAIIGD 189
            .:.|:.|:||::..|||:||.|||:|..:.|| |..|...||:.||||||..|:|:||.:.|:||
Zfish   136 QVFQLISKKKSLGTAAQLLLKGAEKLSKSVSENQEQRRQRDFNSELLRLRSQWKLRKVGDKILGD 200

  Fly   190 LSYRTAGSKFGMSGTFEVTKAEETGDEDTASSSNSSSSVSGNNGMQLKAS-----SALRVIVPAE 249
            ||||:|||.|...|||||.|                     |..:.|...     ..|.|.:|::
Zfish   201 LSYRSAGSLFPHHGTFEVIK---------------------NTDIDLDKKIPDDYCPLNVQIPSD 244

  Fly   250 LQGVAYIKVITQKDQEDL-CTAQLNLMGHGPNITAQVGVWQKTLEFAQNVLFCKELFAQLAREAI 313
            |:|.|||||..||...|: ....:||............:|...||.|||||.|||:||||:|||:
Zfish   245 LEGSAYIKVSIQKQSPDIGDLGTVNLFRRQAKAKPASQMWHSRLEAAQNVLLCKEIFAQLSREAV 309

  Fly   314 QLQAPIPHVVIGNQIRATLLPNIQLIISLCHST--------TFDSSQPAPINDHDHVLEHSLHQL 370
            |:::.|||:|:.|||.:...|.:||.|||||||        :.|.|:|   :||.:||||:||||
Zfish   310 QIKSQIPHIVVKNQIISQPFPGLQLSISLCHSTGEKKSQRSSPDKSKP---DDHLYVLEHNLHQL 371

  Fly   371 LREVHYKN-SHHPFPHPASAPLGPTKKRMLAGPMAADRETLLDMTKSQTILEQIIAQAQHIFMRK 434
            :||.|.:. |....|||||||.| .|:..||||:|.|:..:..:.:::.:||:||.||:|||:|.
Zfish   372 IREFHKQTLSSVVMPHPASAPFG-HKRLRLAGPLAYDKAEISSLQQTEGLLEKIIKQAKHIFLRS 435

  Fly   435 RTQYVLDTLARDVKDPQIVSHWNAMNSPTMSCVKINIVTHGYDAIGRT-SLVIHVKERSLKCICR 498
            ||...:|:||..::||||.:||:.:|....|.||:.|.:.||:.|.:: .|.:::....::.:.|
Zfish   436 RTARTIDSLASRIEDPQIQAHWSNINDVYESSVKVLITSQGYEQICKSIQLQLNICVEQIRVVHR 500

  Fly   499 DGRVMRLSYEPQELRDLILCQINSHQISCLISLARCMSWTVLSNSNHLGIGKVEPLGNASSCLLA 563
            ||||:.||::.|||:|.:|.|::.||:..:..||:.|.|.|||.|||:|:|.:|.:|||||..:|
Zfish   501 DGRVITLSHQEQELQDFLLSQMSQHQVHAVQQLAKVMGWHVLSFSNHVGLGSIESIGNASSITVA 565

  Fly   564 SPNSDRMIAVQIRCDPQIDVKVYI--ARSPRQDFFPSPLVPEKLWENLGGTFKEVRFDKIEGKSF 626
            ||:.:  .|:.:|..|:...||.:  .||..:|...|..|.:..|..|.|..:||.:|::|||:|
Zfish   566 SPSGE--YAISVRNGPESGCKVLVQFPRSQAKDAGRSDAVQDGKWTQLRGAHREVHWDRMEGKNF 628

  Fly   627 LNKMEFLMASLT 638
            :.|||.|||:||
Zfish   629 VYKMELLMAALT 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MED17	NP_650686.1	Med17	<289..390	CDD:287165	57/109 (52%)
med17	NP_001071042.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	53..82		5/28 (18%)
		Med17	<143..427	CDD:287165	133/308 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	185	1.000	Domainoid score	I3336
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3151
Inparanoid	1	1.050	492	1.000	Inparanoid score	I1368
OMA	1	1.010	-	-		QHG49235
OrthoDB	1	1.010	-	-		D414603at33208
OrthoFinder	1	1.000	-	-		FOG0007468
OrthoInspector	1	1.000	-	-		oto39508
orthoMCL	1	0.900	-	-		OOG6_104213
Panther	1	1.100	-	-	LDO	PTHR13114
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2632
SonicParanoid	1	1.000	-	-		X5596
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	13.010